Evaluation of mucoadhesive hydrogels loaded with diclofenac sodium–chitosan microspheres for rectal administration
ES El-Leithy, DS Shaker, MK Ghorab… - Aaps Pharmscitech, 2010 - Springer
Considering the advantageous for the rectal administration of non-steroidal anti-
inflammatory drugs, the objective of this study was to formulate and evaluate rectal …
inflammatory drugs, the objective of this study was to formulate and evaluate rectal …
Nanoemulsions loaded Carbopol® 934 based gel for intranasal delivery of neuroprotective Centella asiatica extract: in–vitro and ex–vivo permeation study
The objective of the present study was to develop a formulation for sustained release of
phytotherapeutics through nasal membrane for brain targeting (anti-Alzheimer) in order to …
phytotherapeutics through nasal membrane for brain targeting (anti-Alzheimer) in order to …
In vitro permeation and biological activity of punicalagin and zinc (II) across skin and mucous membranes prone to Herpes simplex virus infection
Coadministration of pomegranate rind extract (PRE) and zinc (II) ions has recently been
reported as a potential new topical treatment for Herpes simplex virus (HSV) infections. In …
reported as a potential new topical treatment for Herpes simplex virus (HSV) infections. In …
[PDF][PDF] Applications of hydrogels 14
MJ Majcher, T Hoare - Funct. Biopolym, 2019 - researchgate.net
Hydrogels offer multiple unique properties in terms of their porosities, mechanics, interfacial
dynamics, and biological responses that make them highly relevant to a broad range of …
dynamics, and biological responses that make them highly relevant to a broad range of …
Preservatives in Pharmaceuticals: Are They Really Safe?
M Kumar, S Chopra, UK Mandal… - Current Drug Safety, 2023 - ingentaconnect.com
Preservatives are the ingredients that are utilized in order to improve the shelf life of
products (Medicines, food). These tend to slow down or stop the degradation or …
products (Medicines, food). These tend to slow down or stop the degradation or …
Hydrogel thickened microemulsion; a local cargo for the co-delivery of cinnamaldehyde and berberine to treat acne vulgaris
For the existence in an advancing world of antibiotics, bacteria struggle and make necessary
changes at genetic level. This study was designed to deliver a combination of …
changes at genetic level. This study was designed to deliver a combination of …
Assessment of Lemon Balm (Melissa officinalis L.) Hydrogels: Quality and Bioactivity in Skin Cells
K Ramanauskienė, A Stelmakiene… - Evidence‐Based …, 2015 - Wiley Online Library
The aim of the study was to design gels with lemon balm extract, assess their quality, and
investigate the effect of rosmarinic acid on skin cells in normal conditions and under …
investigate the effect of rosmarinic acid on skin cells in normal conditions and under …
Formulation of oxybutynin chloride microparticle-loaded suppositories: in vitro characterization and in vivo pharmacokinetic study
Background Oxybutynin chloride (OXC) is used to treat overactive urinary bladder. OXC is
metabolized in the liver to N-desethyloxybutynin, which is mainly responsible for the …
metabolized in the liver to N-desethyloxybutynin, which is mainly responsible for the …
[HTML][HTML] Infant formula as a solid lipid dose form for enhancement of the oral bioavailability of cannabidiol for paediatric patients
S Huang, AC Pham, M Salim, T Eason… - International Journal of …, 2024 - Elsevier
Cannabinoids can save paediatric patients from harmful psychological conditions caused by
epilepsy. However, the limited aqueous solubility of the drug presents a limitation to oral …
epilepsy. However, the limited aqueous solubility of the drug presents a limitation to oral …
Development and Characterization of a Novel Mucoadhesive sol-gel Suppository of Sumatriptan: design, optimization, In Vitro and Ex Vivo Evaluation for Rectal …
Aim: Sumatriptan (ST) is used for the treatment of migraine and cluster headaches.
However, it exhibits low oral bioavailability (15%) due to the high first-pass metabolism. The …
However, it exhibits low oral bioavailability (15%) due to the high first-pass metabolism. The …