Glutamatergic neurometabolite levels in major depressive disorder: a systematic review and meta-analysis of proton magnetic resonance spectroscopy studies
S Moriguchi, A Takamiya, Y Noda, N Horita… - Molecular …, 2019 - nature.com
Alterations in glutamatergic neurotransmission are implicated in the pathophysiology of
depression, and the glutamatergic system represents a treatment target for depression. To …
depression, and the glutamatergic system represents a treatment target for depression. To …
Glutamate and GABA homeostasis and neurometabolism in major depressive disorder
Major depressive disorder (MDD) is a leading cause of distress, disability, and suicides. As
per the latest WHO report, MDD affects more than 260 million people worldwide. Despite …
per the latest WHO report, MDD affects more than 260 million people worldwide. Despite …
Right care, first time: a highly personalised and measurement‐based care model to manage youth mental health
Mood and psychotic syndromes most often emerge during adolescence and young
adulthood, a period characterised by major physical and social change. Consequently, the …
adulthood, a period characterised by major physical and social change. Consequently, the …
Neurobiological mechanisms of stress resilience and implications for the aged population
C Faye, JC McGowan, CA Denny… - Current …, 2018 - ingentaconnect.com
Background: Stress is a common reaction to an environmental adversity, but a dysregulation
of the stress response can lead to psychiatric illnesses such as major depressive disorder …
of the stress response can lead to psychiatric illnesses such as major depressive disorder …
Role of glutamatergic system and mesocorticolimbic circuits in alcohol dependence
F Alasmari, S Goodwani, RE McCullumsmith… - Progress in …, 2018 - Elsevier
Emerging evidence demonstrates that alcohol dependence is associated with dysregulation
of several neurotransmitters. Alterations in dopamine, glutamate and gamma-aminobutyric …
of several neurotransmitters. Alterations in dopamine, glutamate and gamma-aminobutyric …
A review of the neurobiological underpinning of comorbid substance use and mood disorders
N Gómez-Coronado, R Sethi, CC Bortolasci… - Journal of Affective …, 2018 - Elsevier
Background There is evidence that substance use disorders and other mental disorders may
have shared biological mechanisms. However, the neurobiological basis of this comorbidity …
have shared biological mechanisms. However, the neurobiological basis of this comorbidity …
Transdiagnostic role of glutamate and white matter damage in neuropsychiatric disorders: A Systematic Review
I Luttenbacher, A Phillips, R Kazemi… - Journal of Psychiatric …, 2022 - Elsevier
Neuropsychiatric disorders including generalized anxiety disorder (GAD), obsessive-
compulsive disorder (OCD), major depressive disorder (MDD), bipolar disorder (BD), and …
compulsive disorder (OCD), major depressive disorder (MDD), bipolar disorder (BD), and …
Ethanol-associated changes in glutamate reward neurocircuitry: a minireview of clinical and preclinical genetic findings
Herein, we have reviewed the role of glutamate, the major excitatory neurotransmitter in the
brain, in a number of neurochemical,-physiological, and-behavioral processes mediating the …
brain, in a number of neurochemical,-physiological, and-behavioral processes mediating the …
Commonality of Ethanol and Nicotine Reinforcement and Relapse in Wistar‐Derived UChB Rats: Inhibition by N‐Acetylcysteine
Background Life expectancy is greatly reduced in individuals presenting alcohol use
disorders and chronic smoking. Literature studies suggest that common mechanisms may …
disorders and chronic smoking. Literature studies suggest that common mechanisms may …
Effects of l-theanine on anxiety-like behavior, cerebrospinal fluid amino acid profile, and hippocampal activity in Wistar Kyoto rats
S Ogawa, M Ota, J Ogura, K Kato, H Kunugi - Psychopharmacology, 2018 - Springer
Rationale and objectives The amino acid l-theanine (N-ethyl-l-glutamine) has historically
been considered a relaxing agent. In the present study, we examined the effects of repeated …
been considered a relaxing agent. In the present study, we examined the effects of repeated …