Abstract The Sequential Organ Failure Assessment or SOFA score was developed to assess
the acute morbidity of critical illness at a population level and has been widely validated as a …

Background Missing data are common in longitudinal studies, and more so, in studies of
older adults, who are susceptible to health and functional decline that limit completion of …

Importance Traumatic brain injury (TBI) affects millions of people in the US each year. Most
patients with TBI seen in emergency departments (EDs) have a Glasgow Coma Scale (GCS) …

Background and Objectives The objectives of this study were to develop and establish
concurrent validity of a clinically relevant definition of poor cognitive outcome 1 year after …

Objective Cognitive impairment is a key cause of disability after traumatic brain injury (TBI)
but relationships with overall functioning in daily life are often modest. The aim is to examine …

Background An improved understanding of the trajectory of recovery after mild traumatic
brain injury is important to be able to understand individual patient outcomes, for …

Importance Persistent symptoms after mild traumatic brain injury (mTBI) represent a major
public health problem. Objective To identify neuroanatomical substrates of mTBI and the …

Background and Objective Nearly one-third of patients with severe traumatic brain injury
(TBI) develop posttraumatic epilepsy (PTE). The relationship between PTE and long-term …

Loss to follow-up and missing outcomes data are important issues for longitudinal
observational studies and clinical trials in traumatic brain injury. One popular solution to …

Objective Posttraumatic epilepsy (PTE) develops in as many as one third of severe traumatic
brain injury (TBI) patients, often years after injury. Analysis of early electroencephalographic …