Gene–environment interactions in Alzheimer disease: the emerging role of epigenetics
L Migliore, F Coppedè - Nature Reviews Neurology, 2022 - nature.com
With the exception of a few monogenic forms, Alzheimer disease (AD) has a complex
aetiology that is likely to involve multiple susceptibility genes and environmental factors. The …
aetiology that is likely to involve multiple susceptibility genes and environmental factors. The …
Nutrition and prevention of cognitive impairment
N Scarmeas, CA Anastasiou… - The Lancet Neurology, 2018 - thelancet.com
Nutrition is an important lifestyle factor that can modify the risk of future cognitive impairment
and dementia. Some, but not conclusive, evidence (mostly from observational studies and …
and dementia. Some, but not conclusive, evidence (mostly from observational studies and …
A fiber-deprived diet causes cognitive impairment and hippocampal microglia-mediated synaptic loss through the gut microbiota and metabolites
Background Cognitive impairment, an increasing mental health issue, is a core feature of the
aging brain and neurodegenerative diseases. Industrialized nations especially, have …
aging brain and neurodegenerative diseases. Industrialized nations especially, have …
Antibiotics, gut microbiota, and Alzheimer's disease
F Angelucci, K Cechova, J Amlerova, J Hort - Journal of neuroinflammation, 2019 - Springer
Alzheimer's disease (AD) is a neurodegenerative disease whose various pathophysiological
aspects are still being investigated. Recently, it has been hypothesized that AD may be …
aspects are still being investigated. Recently, it has been hypothesized that AD may be …
Alzheimer's disease and gut microbiota
X Hu, T Wang, F Jin - Science China Life Sciences, 2016 - Springer
Alzheimer's disease (AD) is a most common neurodegenerative disorder, which associates
with impaired cognition. Gut microbiota can modulate host brain function and behavior via …
with impaired cognition. Gut microbiota can modulate host brain function and behavior via …
Diet in the prevention of Alzheimer's disease: current knowledge and future research requirements
O Stefaniak, M Dobrzyńska, S Drzymała-Czyż… - Nutrients, 2022 - mdpi.com
Alzheimer's disease is a progressive brain disease that is becoming a major health problem
in today's world due to the aging population. Despite it being widely known that diet has a …
in today's world due to the aging population. Despite it being widely known that diet has a …
[HTML][HTML] Intakes of fish and polyunsaturated fatty acids and mild-to-severe cognitive impairment risks: a dose-response meta-analysis of 21 cohort studies
Y Zhang, J Chen, J Qiu, Y Li, J Wang, J Jiao - The American journal of …, 2016 - Elsevier
Background: The intake of fish and polyunsaturated fatty acids (PUFAs) may benefit
cognitive function. However, optimal intake recommendations for protection are unknown …
cognitive function. However, optimal intake recommendations for protection are unknown …
Epidemiology of Alzheimer's disease: occurrence, determinants, and strategies toward intervention
C Qiu, M Kivipelto, E Von Strauss - Dialogues in clinical …, 2009 - Taylor & Francis
More than 25 million people in the world today are affected by dementia, most suffering from
Alzheimer's disease. In both developed and developing nations, Alzheimer's disease has …
Alzheimer's disease. In both developed and developing nations, Alzheimer's disease has …
The amyloid cascade-inflammatory hypothesis of Alzheimer disease: implications for therapy
PL McGeer, EG McGeer - Acta neuropathologica, 2013 - Springer
The amyloid cascade hypothesis is widely accepted as the centerpiece of Alzheimer
disease (AD) pathogenesis. It proposes that abnormal production of beta amyloid protein …
disease (AD) pathogenesis. It proposes that abnormal production of beta amyloid protein …
MIND diet and cognitive performance in older adults: a systematic review
S Kheirouri, M Alizadeh - Critical reviews in food science and …, 2022 - Taylor & Francis
Cognitive decline is a rapidly increasing public health concern. A healthy diet has potential
in preserving brain and maintaining cognitive health. This systematic review was designed …
in preserving brain and maintaining cognitive health. This systematic review was designed …