Molecular and circulating biomarkers in patients with glioblastoma

N Senhaji, A Squalli Houssaini, S Lamrabet… - International Journal of …, 2022 - mdpi.com
Glioblastoma is the most aggressive malignant tumor of the central nervous system with a
low survival rate. The difficulty of obtaining this tumor material represents a major limitation …

Epigenetic underpinnings of inflammation: a key to unlock the tumor microenvironment in glioblastoma

N Chen, C Peng, D Li - Frontiers in Immunology, 2022 - frontiersin.org
Glioblastoma (GBM) is the most common malignant brain tumor in adults, and
immunotherapies and genetic therapies for GBM have evolved dramatically over the past …

Multiple therapeutic approaches of glioblastoma multiforme: From terminal to therapy

S Kumari, R Gupta, RK Ambasta, P Kumar - Biochimica et Biophysica Acta …, 2023 - Elsevier
Glioblastoma multiforme (GBM) is an aggressive brain cancer showing poor prognosis.
Currently, treatment methods of GBM are limited with adverse outcomes and low survival …

[HTML][HTML] PD-L1-related IncRNAs are associated with malignant characteristics and immune microenvironment in glioma

Z Xia, R Tu, F Liu, H Zhang, Z Dai, Z Wang… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Background: The expression of long non-coding RNA (lncRNA) can function as diagnostic
and therapeutic biomarker for tumors. This research explores the role of PD-L1-related …

lncRNA KTN1‑AS1 promotes glioma cell proliferation and invasion by negatively regulating miR‑505‑3p

Y Mu, Q Tang, H Feng, L Zhu… - Oncology …, 2020 - spandidos-publications.com
Glioblastoma (GBM) is one of the most prevalent and aggressive central nervous tumors
with high mobility and mortality. The prognosis of patients with GBM is poor. It is therefore …

The multifaceted role of extracellular vesicles in glioblastoma: microRNA nanocarriers for disease progression and gene therapy

N Simionescu, R Zonda, AR Petrovici, A Georgescu - Pharmaceutics, 2021 - mdpi.com
Glioblastoma (GB) is the most aggressive form of brain cancer in adults, characterized by
poor survival rates and lack of effective therapies. MicroRNAs (miRNAs) are small, non …

Insights into the roles of non-coding RNAs and angiogenesis in glioblastoma: An overview of current research and future perspectives

Z Song, Z Xue, Y Wang, M Imran, M Assiri… - Biochimica et Biophysica …, 2024 - Elsevier
Glioblastoma (GBM) is a highly aggressive type of primary brain cancer with a poor
prognosis, and despite intensive research, survival rates have not significantly improved …

[HTML][HTML] LINC01393, a Novel Long Non-Coding RNA, Promotes the Cell Proliferation, Migration and Invasion through MiR-128-3p/NUSAP1 Axis in Glioblastoma

D Li, J Hu, S Li, C Zhou, M Feng, L Li, Y Gao… - International Journal of …, 2023 - mdpi.com
Nucleolar and spindle-associated protein 1 (NUSAP1) is a potential molecular marker and
intervention target for glioblastoma (GBM). In this study, we aim to investigate upstream …

H2S-mediated inhibition of RhoA/ROCK pathway and noncoding RNAs in ischemic stroke

W Lu, J Wen - Metabolic Brain Disease, 2023 - Springer
Ischemic stroke is one of major causes of disability. In the pathological process of ischemic
stroke, the up-regulation of Ras homolog gene family, member A (RhoA) and its downstream …

New perspective on DNA response pathway (DDR) in glioblastoma, focus on classic biomarkers and emerging roles of ncRNAs

BO Pirlog, S Ilut, R Pirlog, P Chiroi, A Nutu… - Expert Reviews in …, 2023 - cambridge.org
Background Glioblastoma (GBM) is the most frequent type of primary brain cancer, having a
median survival of only 15 months. The current standard of care includes a combination of …