The ability to design nanostructures with arbitrary shapes and controllable motions has
made DNA nanomaterials used widely to construct diverse nanomachines with various …

The molecular biomarkers are molecules that are closely related to specific physiological
states. Numerous molecular biomarkers have been identified as targets for disease …

A molecular classification of diseases that accurately reflects clinical behaviour lays the
foundation of precision medicine. The development of in silico classifiers coupled with …

Nucleic acids are natural biopolymers of nucleotides that store, encode, transmit and
express genetic information, which play central roles in diverse cellular events and diseases …

Accurate detection and imaging of tumor-related microRNA (miRNA) in living cells hold
great promise for early cancer diagnosis and prognosis. One of the challenges is to develop …

Fluorescent biosensors have been widely applied in DNA detection because of their
reliability and reproducibility. However, low kinetics in DNA hybridization often brings out …

The trans‐cleavage property of CRISPR‐Cas12a system makes it an excellent tool for
disease diagnosis. Nevertheless, most methods based on CRISPR‐Cas system still require …

Accurate and population-scale screening technology is crucial in the control and prevention
of COVID-19, such as pooled testing with high overall testing efficiency. Nevertheless …

Mass pathogen screening is critical to preventing the outbreaks and spread of infectious
diseases. The large‐scale epidemic of COVID‐19 and the rapid mutation of the severe acute …

The interfacial mass transfer rate of a target has a significant impact on the sensing
performance. The surface reaction forms a concentration gradient perpendicular to the …