Plasmids contain a backbone of core genes that remains relatively stable for long
evolutionary periods, making sense to speak about plasmid species. The identification and …

Escherichia coli and other Gram-negative and-positive bacteria employ type IV secretion
systems (T4SSs) to translocate DNA and protein substrates, generally by contact-dependent …

Large conjugative plasmids are important drivers of bacterial evolution and contribute
significantly to the dissemination of antibiotic resistance. Although plasmid borne multidrug …

Antibiotic resistance encoded on plasmids is a pressing global health problem. Predicting
which plasmids spread in the long term remains very challenging, even though some key …

Antibiotic resistance arises from the maintenance of resistance mutations or genes acquired
from the acquisition of adaptive de novo mutations or the transfer of resistance genes …

The gut microbiota is a suspected hotspot for bacterial conjugation due to its high density
and diversity of microorganisms. However, the contribution of different conjugative plasmid …

Plasmids, extrachromosomal DNA molecules commonly found in bacterial and archaeal
cells, play an important role in bacterial genetics and evolution. Our understanding of …

Plasmids are mobile genetic elements that play a key role in microbial ecology and
evolution by mediating horizontal transfer of important genes, such as antimicrobial …

Elucidating the adaptive strategies and plasticity of bacterial genomes in situ is crucial for
understanding the epidemiology and evolution of pathogens threatening human health …

Plasmids are ubiquitous in the microbial world and have been identified in almost all
species of bacteria that have been examined. Their localization inside the bacterial cell has …