Pulmonary hypertension (PH) is a progressive lethal disease, which is characterized by
abnormal vascular remodeling and persistently elevated pulmonary artery pressure …

Study Objectives: The unique pathophysiologic contributions of obstructive sleep apnea
(OSA) toward pulmonary hypertension and right ventricular (RV) dysfunction still represent …

Background Hyperuricemia and right ventricular dysfunction (RVD) are both widespread in
heart failure with preserved ejection fraction (HFpEF) patients. RVD is associated with a …

Backgrounds: Hypertension stands as the predominant global cause of mortality. A notable
deficiency exists in terms of predictive models for mortality among individuals with …

With the progress in diagnosis, treatment and imaging techniques, there is a growing
recognition that impaired right ventricular (RV) function profoundly affects the prognosis of …

To evaluate the association of uric acid (UA) with adverse outcomes and its potential
mediator in patients with left ventricular diastolic dysfunction (LVDD) and pulmonary …

Abstract Background Extrachromosomal circular DNAs (eccDNAs) have been reported to
play a key role in the occurrence and development of various diseases. However, the …

Purpose Patients with pulmonary arterial hypertension (PAH) are at high risk for obstructive
sleep apnea (OSA), which may adversely affect pulmonary hemodynamics and long-term …

Asymptomatic hyperuricemia is defined by serum uric acid levels above 6.2 mg/dl in women
and 7 mg/dl in men. In the presence of monosodium urate crystal formation and articular …

Pulmonary hypertension (PH) is a severe form of pulmonary vascular disease that can lead
to right heart failure (RHF). Nearly 2-thirds of patients with PH die within 5 years. Studies …