Anticancer peptides mechanisms, simple and complex

P Norouzi, M Mirmohammadi, MHH Tehrani - Chemico-Biological …, 2022 - Elsevier
Peptide therapy has started since 1920s with the advent of insulin application, and now it
has emerged as a new approach in treatment of diseases including cancer. Using anti …

Changes in interstitial fluid flow, mass transport and the bone cell response in microgravity and normogravity

F Wei, K Flowerdew, M Kinzel, LE Perotti, J Asiatico… - Bone Research, 2022 - nature.com
In recent years, our scientific interest in spaceflight has grown exponentially and resulted in
a thriving area of research, with hundreds of astronauts spending months of their time in …

Glucose metabolism and glycosylation link the gut microbiota to autoimmune diseases

L Wang, H Xu, H Yang, J Zhou, L Zhao… - Frontiers in …, 2022 - frontiersin.org
Carbohydrates serve as important energy sources and structural substances for human
body as well as for gut microbes. As evidenced by the advances in immunometabolism …

[HTML][HTML] A comprehensive review on modeling aspects of infusion-based drug delivery in the brain

T Yuan, W Zhan, M Terzano, GA Holzapfel, D Dini - Acta Biomaterialia, 2024 - Elsevier
Brain disorders represent an ever-increasing health challenge worldwide. While
conventional drug therapies are less effective due to the presence of the blood-brain barrier …

Microbial strategies for oil biodegradation

GE Kapellos - Modeling of microscale transport in biological …, 2017 - Elsevier
The current understanding of the fundamental microscale mechanisms that underlie the
biodegradation of oily substrates by microbial communities is concisely reviewed in this …

Impact of microbial uptake on the nutrient plume around marine organic particles: High-resolution numerical analysis

GE Kapellos, HJ Eberl, N Kalogerakis, PS Doyle… - Microorganisms, 2022 - mdpi.com
The interactions between marine bacteria and particulate matter play a pivotal role in the
biogeochemical cycles of carbon and associated inorganic elements in the oceans …

Good coupling for the multiscale patch scheme on systems with microscale heterogeneity

JE Bunder, AJ Roberts, IG Kevrekidis - Journal of Computational Physics, 2017 - Elsevier
Computational simulation of microscale detailed systems is frequently only feasible over
spatial domains much smaller than the macroscale of interest. The 'equation …

Phagocytosis: sweet repulsions via the glycocalyx

S Maschalidi, KS Ravichandran - Current Biology, 2021 - cell.com
New work shows that the glycocalyx meshwork on the surface of macrophages prevents
phagocytic receptors from binding their ligands by two means—electrostatic charge and …

Tenomodulin and Chondromodulin-1 Are Both Required to Maintain Biomechanical Function and Prevent Intervertebral Disc Degeneration

T Di Pauli von Treuheim, OM Torre, ED Ferreri… - Cartilage, 2021 - journals.sagepub.com
Objective The underlying mechanisms and molecular factors influencing intervertebral disc
(IVD) homeostasis and degeneration remain clinically relevant. Tenomodulin (Tnmd) and …

Magnetic Resonance Relaxation in Heterogeneous Materials is Analogous to First-Order Chemical Reaction

A Afrough - Transport in Porous Media, 2024 - Springer
Biological tissue, pharmaceutical tablets, wood, porous rocks, catalytic reactors, concrete,
and foams are examples of heterogeneous systems that may contain one or several fluid …