[HTML][HTML] Hereditary hemorrhagic telangiectasia: diagnosis and management from the hematologist's perspective

A Kritharis, H Al-Samkari, DJ Kuter - Haematologica, 2018 - ncbi.nlm.nih.gov
Hereditary hemorrhagic telangiectasia (HHT), also known as Osler-Weber-Rendu
syndrome, is an autosomal dominant disorder that causes abnormal blood vessel formation …

Hereditary hemorrhagic telangiectasia: systemic therapies, guidelines, and an evolving standard of care

H Al-Samkari - Blood, The Journal of the American Society of …, 2021 - ashpublications.org
Hereditary hemorrhagic telangiectasia (HHT) management is evolving because of the
emergence and development of antiangiogenic therapies to eliminate bleeding …

Second international guidelines for the diagnosis and management of hereditary hemorrhagic telangiectasia

ME Faughnan, JJ Mager, SW Hetts… - Annals of internal …, 2020 - acpjournals.org
Description: Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant
disease with an estimated prevalence of 1 in 5000 that is characterized by the presence of …

Intravenous bevacizumab for refractory hereditary hemorrhagic telangiectasia–related epistaxis and gastrointestinal bleeding

VN Iyer, DR Apala, BS Pannu, A Kotecha… - Mayo Clinic …, 2018 - Elsevier
Objective To present a multiyear clinical experience with intravenous bevacizumab for the
management of severe gastrointestinal bleeding and/or epistaxis in patients with hereditary …

Efficacy and safety of intravenous bevacizumab on severe bleeding associated with hemorrhagic hereditary telangiectasia: a national, randomized multicenter trial

S Dupuis‐Girod, S Rivière, C Lavigne… - Journal of Internal …, 2023 - Wiley Online Library
Background Bevacizumab—a humanized monoclonal antibody—has been widely used to
treat patients with hereditary hemorrhagic telangiectasia (HHT), but no randomized trial has …

Effect of topical intranasal therapy on epistaxis frequency in patients with hereditary hemorrhagic telangiectasia: a randomized clinical trial

KJ Whitehead, NB Sautter, JP McWilliams… - Jama, 2016 - jamanetwork.com
Importance Epistaxis is a major factor negatively affecting quality of life in patients with
hereditary hemorrhagic telangiectasia (HHT; also known as Osler-Weber-Rendu disease) …

European Reference Network for Rare Vascular Diseases (VASCERN): when and how to use intravenous bevacizumab in hereditary haemorrhagic telangiectasia …

S Dupuis-Girod, CL Shovlin, AD Kjeldsen… - European Journal of …, 2022 - Elsevier
Hereditary haemorrhagic telangiectasia (HHT) is a rare vascular multisystemic disease that
leads to epistaxis, anaemia due to blood loss, and arteriovenous malformations (AVMs) in …

Systemic bevacizumab for the treatment of chronic bleeding in hereditary haemorrhagic telangiectasia

H Al‐Samkari, A Kritharis… - Journal of internal …, 2019 - Wiley Online Library
Background Hereditary haemorrhagic telangiectasia (HHT) is a rare hereditary multisystem
vascular disorder causing visceral arteriovenous malformations and mucocutaneous …

Intra-venous bevacizumab in hereditary hemorrhagic telangiectasia (HHT): A retrospective study of 46 patients

A Guilhem, AE Fargeton, AC Simon, P Duffau… - PLoS …, 2017 - journals.plos.org
Background Bevacizumab, an anti-VEGF monoclonal antibody, has recently emerged as a
new option for severe forms of hereditary hemorrhagic telangiectasia (HHT). Its utilization in …

Etiology and genetics of congenital vascular lesions

A Queisser, LM Boon, M Vikkula - Otolaryngologic clinics of North …, 2018 - oto.theclinics.com
Etiology and Genetics of Congenital Vascular Lesions - Otolaryngologic Clinics of North
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