Host-directed antiviral therapy

N Kumar, S Sharma, R Kumar, BN Tripathi… - Clinical microbiology …, 2020 - Am Soc Microbiol
Antiviral drugs have traditionally been developed by directly targeting essential viral
components. However, this strategy often fails due to the rapid generation of drug-resistant …

Dietary phytochemicals as epigenetic modifiers in cancer: Promise and challenges

E Shankar, R Kanwal, M Candamo, S Gupta - Seminars in cancer biology, 2016 - Elsevier
The influence of diet and environment on human health has been known since ages. Plant-
derived natural bioactive compounds (phytochemicals) have acquired an important role in …

Quercetin modifies 5′ CpG promoter methylation and reactivates various tumor suppressor genes by modulating epigenetic marks in human cervical cancer cells

M Kedhari Sundaram, A Hussain… - Journal of cellular …, 2019 - Wiley Online Library
The central role of epigenomic alterations in carcinogenesis has been widely
acknowledged, particularly the impact of DNA methylation on gene expression across all …

Tumor markers of uterine cervical cancer: a new scenario to guide surgical practice?

G Valenti, SG Vitale, A Tropea, A Biondi, AS Laganà - Updates in surgery, 2017 - Springer
Since the introduction of Pap smear screening, the incidence and mortality of cervical cancer
(CC) have been reduced drastically in USA and in other western states. Nevertheless, CC …

Molecular markers for cervical cancer screening

C Güzel, J van Sten-van't Hoff… - Expert review of …, 2021 - Taylor & Francis
This review gives an overview of current screening practices for cervical cancer. In the
introduction, we will cover approaches of population screening focusing on high-risk Human …

Molecular landscape of recurrent cervical cancer

D Adiga, S Eswaran, D Pandey, K Sharan… - Critical Reviews in …, 2021 - Elsevier
Cervical cancer (CC) is a major gynecological problem in developing and underdeveloped
countries. Despite the significant advancement in early detection and treatment modalities …

Dietary isothiocyanates inhibit cancer progression by modulation of epigenome

MK Sundaram, R Preetha, S Haque, N Akhter… - Seminars in Cancer …, 2022 - Elsevier
Cell cycle, growth, survival and metabolism are tightly regulated together and failure in
cellular regulation leads to carcinogenesis. Several signaling pathways like the PI3K, WNT …

[HTML][HTML] Modulation of DNA methylation by human papillomavirus E6 and E7 oncoproteins in cervical cancer

P Sen, P Ganguly, N Ganguly - Oncology letters, 2018 - spandidos-publications.com
Human papillomaviruses (HPVs) are double stranded circular DNA viruses that infect
cutaneous and mucosal epithelial cells. Almost 99% of cervical cancer has a HPV infection …

[HTML][HTML] Advances in epigenetic modifications and cervical cancer research

H Liu, H Ma, Y Li, H Zhao - Biochimica et Biophysica Acta (BBA)-Reviews …, 2023 - Elsevier
Cervical cancer (CC) is an important public health problem for women, and perspectives
and information regarding its prevention and treatment are quickly evolving. Human …

Cervical cancer in pregnancy: Analysis of the literature and innovative approaches

AM Perrone, A Bovicelli, G D'Andrilli… - Journal of Cellular …, 2019 - Wiley Online Library
Cervical cancer is one of the most common gynecological malignancies diagnosed during
pregnancy although, fortunately, it is a rare event. In majority of cases, the management of …