[HTML][HTML] Creatine in health and disease

RB Kreider, JR Stout - Nutrients, 2021 - mdpi.com
Although creatine has been mostly studied as an ergogenic aid for exercise, training, and
sport, several health and potential therapeutic benefits have been reported. This is because …

[HTML][HTML] Metabolic basis of creatine in health and disease: a bioinformatics-assisted review

DA Bonilla, RB Kreider, JR Stout, DA Forero… - Nutrients, 2021 - mdpi.com
Creatine (Cr) is a ubiquitous molecule that is synthesized mainly in the liver, kidneys, and
pancreas. Most of the Cr pool is found in tissues with high-energy demands. Cr enters target …

[HTML][HTML] Creatine supplementation, physical exercise and oxidative stress markers: a review of the mechanisms and effectiveness

H Arazi, E Eghbali, K Suzuki - Nutrients, 2021 - mdpi.com
Oxidative stress is the result of an imbalance between the generation of reactive oxygen
species (ROS) and their elimination by antioxidant mechanisms. ROS degrade biogenic …

Nutraceuticals and COVID‐19: a mechanistic approach toward attenuating the disease complications

KR Paudel, V Patel, S Vishwas, S Gupta… - Journal of Food …, 2022 - Wiley Online Library
Nutraceuticals have emerged as potential compounds to attenuate the COVID‐19
complications. Precisely, these food additives strengthen the overall COVID treatment and …

[HTML][HTML] Exploring the role of nutraceuticals in major depressive disorder (MDD): Rationale, state of the art and future prospects

MA Alvarez-Mon, MA Ortega, C García-Montero… - Pharmaceuticals, 2021 - mdpi.com
Major depressive disorder (MDD) is a complex and common disorder, with many factors
involved in its onset and development. The clinical management of this condition is …

[HTML][HTML] The potential role of creatine in vascular health

H Clarke, RC Hickner, MJ Ormsbee - Nutrients, 2021 - mdpi.com
Creatine is an organic compound, consumed exogenously in the diet and synthesized
endogenously via an intricate inter-organ process. Functioning in conjunction with creatine …

[HTML][HTML] Cardiac oxidative stress and the therapeutic approaches to the intake of antioxidant supplements and physical activity

K Valaei, S Taherkhani, H Arazi, K Suzuki - Nutrients, 2021 - mdpi.com
Reactive oxygen species (ROS) are strongly reactive chemical entities that include oxygen
regulated by enzymatic and non-enzymatic antioxidant defense mechanisms. ROS …

[HTML][HTML] A hypothesis from metabolomics analysis of diabetic retinopathy: arginine-creatine metabolic pathway may be a new treatment strategy for diabetic …

Y Sun, L Kong, AH Zhang, Y Han, H Sun… - Frontiers in …, 2022 - frontiersin.org
Diabetic retinopathy is one of the serious complications of diabetes, which the leading
causes of blindness worldwide, and its irreversibility renders the existing treatment methods …

[HTML][HTML] The use of medications and dietary supplements by masters athletes—a review

J Harnett, M Climstein, J Walsh, J Gifford - Current Nutrition Reports, 2022 - Springer
Abstract Purpose of Review Masters athletes (MA) are generally considered healthier than
their sedentary peers. However, the prevalence of chronic conditions in any population …

Urinary metabolomics profiling by cardiovascular risk factors in young adults: the African Prospective study on Early Detection and Identification of Cardiovascular …

WL du Toit, R Kruger, LF Gafane-Matemane… - Journal of …, 2022 - journals.lww.com
Aim: Risk factors contributes to a dysregulated metabolism and may ultimately increase the
predisposition for cardiovascular disease (CVD) development. To increase our …