Brain metastases are a very common manifestation of cancer that have historically been
approached as a single disease entity given the uniform association with poor clinical …

The incidence of brain metastasis is increasing as improvements in systemic therapy lead to
increased survival. This provides new and challenging clinical decisions for patients who …

Importance For brain metastases, the combination of neurosurgical resection and
postoperative hypofractionated stereotactic radiotherapy (HSRT) is an emerging therapeutic …

Background and objective The ideal delivery of radiation to the surgical cavity of brain
metastases (BMs) remains the subject of debate. Risks of local failure (LF) and radiation …

Simple Summary Brain metastases are of increasing concern in the management of cancer
patients. New systemic treatment options like specific targeting agents or immune …

Despite complete surgical resection brain metastases are at significant risk of local
recurrence without additional radiation therapy. Traditionally, the addition of postoperative …

Since the mid–twentieth century, whole-brain radiation therapy (WBRT) has been used to
treat patients with brain metastases using 2 lateral opposing fields to cover the entire brain …

OBJECTIVE Fluorescence-guided resection of cerebral metastases has been proposed as
an approach to visualize residual tumor tissue and maximize the extent of resection. Critics …

Background The safety and effectiveness of neoadjuvant fractionated stereotactic
radiotherapy (FSRT) before piecemeal resection of brain metastasis (BM) remains unknown …

Background The brain is a common site for cancer metastases. In case of large and/or
symptomatic brain metastases, neurosurgical resection is performed. Adjuvant radiotherapy …