Cadmium (Cd) is a pervasive toxic metal, present in most food types, cigarette smoke, and
air. Most cells in the body will assimilate Cd, as its charge and ionic radius are similar to the …

Heme is an iron-containing prosthetic group necessary for the function of several proteins
termed" hemoproteins." Erythrocytes contain most of the body's heme in the form of …

Heme b (iron protoporphyrin IX) plays important roles in biology as a metallocofactor and
signaling molecule. However, the targets of heme signaling and the network of proteins that …

Heme is a vital cofactor of proteins with roles in oxygen transport (eg hemoglobin), storage
(eg myoglobin), and activation (eg P450) as well as electron transfer (eg cytochromes) and …

Heme regulatory motifs (HRMs) are found in a variety of proteins with diverse biological
functions. In heme oxygenase-2 (HO2), heme binds to the HRMs and is readily transferred to …

Cadmium (Cd) is an environmental toxicant of public health significance worldwide. Diet is
the main Cd exposure source in the non-occupationally exposed and non-smoking …

Obstructive sleep apnea (OSA) is a common breathing disorder that affects a significant
portion of the adult population. In addition to causing excessive daytime sleepiness and …

Oxidative stress and metabolic disorders are involved in the pathogenesis of polycystic
ovary syndrome (PCOS). Heme oxygenase 2 (HMOX2) plays a critical role in preserving …

Heme, an iron-protoporphyrin IX complex, is a cofactor bound to various hemoproteins and
supports a broad range of functions, such as electron transfer, oxygen transport, signal …

Contact-sites are specialized zones of proximity between two organelles, essential for
organelle communication and coordination. The formation of contacts between the …