Rhodanines, thiazolidine-2, 4-diones and pseudothiohydantoins have become a very
interesting class of heterocyclic compounds since the introduction of various glitazones and …

Thiazolidinedione is an important heterocyclic ring system, a pharmacophore and a
privileged scaffold in medicinal chemistry; is a derivative of thiazolidine ring which came into …

The recent discovery that peroxisome proliferator-activated receptor γ (PPARγ) targeted anti-
diabetic drugs function by inhibiting Cdk5-mediated phosphorylation of the receptor has …

Introduction: Acridine derivatives have been extensively explored as potential therapeutic
agents for the treatment of a number of diseases, such as cancer, Alzheimer's, and bacterial …

A series of fourteen novel thiazolidine-2, 4-dione derivatives clubbed with pyrazole moiety
were synthesized via four step reaction procedure. Reactions were monitored by thin layer …

Eight new 5-arylidene-3-benzyl-thiazolidine-2, 4-diones with halide groups on their benzyl
rings were synthesized and assayed in vivo to investigate their anti-inflammatory activities …

The β-phenyl-α, β-unsaturated carbonyl (PUSC) scaffold confers tyrosinase inhibitory
activity, and in the present study, 16 (Z)-5-(substituted benzylidene)-3-phenyl-2 …

Although their exact role in controlling tumour growth and apoptosis in humans remains
undefined, acridine and thiazolidine compounds have been shown to act as tumour …

Type 2 diabetes mellitus is a vast growing progressive disease that almost affects one
person among every twelve globally. Regardless the availability of wide variety of oral …

New arylidene-thiazolidinediones (ATZDs) were synthesized and evaluated in the alloxan-
induced hyperglycemia mice model. The molecular target taken into consideration is the …