Control of the oxygen dependence of an implantable polymer/enzyme composite biosensor for glutamate
Biosensors for glutamate (Glu) were fabricated from Teflon-coated Pt wire (cylinders and
disks), modified with the enzyme glutamate oxidase (GluOx) and electrosynthesized polymer …
disks), modified with the enzyme glutamate oxidase (GluOx) and electrosynthesized polymer …
Mathematical analysis of reaction–diffusion equations modeling the michaelis–menten kinetics in a micro-disk biosensor
In this study, we have investigated the mathematical model of an immobilized enzyme
system that follows the Michaelis–Menten (MM) kinetics for a micro-disk biosensor. The film …
system that follows the Michaelis–Menten (MM) kinetics for a micro-disk biosensor. The film …
Oxygen tolerance of an implantable polymer/enzyme composite glutamate biosensor displaying polycation-enhanced substrate sensitivity
CP McMahon, G Rocchitta, SM Kirwan… - Biosensors and …, 2007 - Elsevier
Biosensors were fabricated at neutral pH by sequentially depositing the polycation
polyethyleneimine (PEI), the stereoselective enzyme l-glutamate oxidase (GluOx) and the …
polyethyleneimine (PEI), the stereoselective enzyme l-glutamate oxidase (GluOx) and the …
Reaction/diffusion equation with Michaelis-Menten kinetics in microdisk biosensor: Homotopy perturbation method approach
R Swaminathan, KL Narayanan, V Mohan… - International Journal of …, 2019 - Elsevier
This paper presents the non steady state model of a microdisk enzyme based biosensor
where the enzyme reacts directly on the electrode itself. The model is based on diffusion …
where the enzyme reacts directly on the electrode itself. The model is based on diffusion …
Glucose diffusivity in cell culture medium
The diaphragm cell method (DCM) was applied to determine the self-diffusion of glucose in
cell culture media (CCM) and water (reference fluid). For this purpose, a diffusion cell based …
cell culture media (CCM) and water (reference fluid). For this purpose, a diffusion cell based …
Mathematical model of whole cell based bio-chip: An electrochemical biosensor for water toxicity detection
Whole cell biosensors, which have been genetically engineered to respond to
environmental stress, trigger a sequence of processes, which leads to generation of …
environmental stress, trigger a sequence of processes, which leads to generation of …
The efficiency of immobilised glutamate oxidase decreases with surface enzyme loading: an electrostatic effect, and reversal by a polycation significantly enhances …
The apparent Michaelis constant, KM, for glutamate oxidase (GluOx) immobilised on Pt
electrodes increased systematically with enzyme loading. The effect was due, at least in …
electrodes increased systematically with enzyme loading. The effect was due, at least in …
A Detailed Model of Electroenzymatic Glutamate Biosensors To Aid in Sensor Optimization and in Applications in Vivo
M Clay, HG Monbouquette - ACS chemical neuroscience, 2018 - ACS Publications
Simulations conducted with a detailed model of glutamate biosensor performance describe
the observed sensor performance well, illustrate the limits of sensor performance, and …
the observed sensor performance well, illustrate the limits of sensor performance, and …
Design variations of a polymer–enzyme composite biosensor for glucose: Enhanced analyte sensitivity without increased oxygen dependence
CP McMahon, SJ Killoran, RD O'Neill - Journal of Electroanalytical …, 2005 - Elsevier
The glucose sensitivity and oxygen dependence of a variety of implantable biosensors
based on glucose oxidase (GOx), incorporating an electrosynthesized poly-o …
based on glucose oxidase (GOx), incorporating an electrosynthesized poly-o …
On glucose diffusivity of tissue engineering membranes and scaffolds
There has been an increasing interest in the concept of growing artificial tissues in
bioreactors which use numerous membranes and scaffolds to support the cellular processes …
bioreactors which use numerous membranes and scaffolds to support the cellular processes …