Evaluating the postprandial response to a dietary challenge containing all macronutrients—
carbohydrates, lipids, and protein—may provide stronger insights of metabolic health than a …

Glucose tolerance represents a complex phenotype in which many tissues play important
roles and interact to regulate metabolic homeostasis. Here, we perform an analysis of 13 C 6 …

The incidence of childhood obesity and metabolic syndrome has grown notably in the last
years, becoming major public health burdens in developed countries. Nowadays, oxidative …

Background Fatty acids play prominent roles in brain function as they participate in
structural, metabolic and signaling processes. The homeostasis of fatty acids and related …

Background Insulin resistance (IR) is considered the main driver of obesity related metabolic
complications, and is related to oxidative stress and inflammation, which in turn promote …

Background Today, obesity affects over one-third of the global population and is hugely
considered the Industrial Revolution's side effect. This multi-factorial disease is continuously …

The circulating metabolome of human peripheral blood provides valuable information to
investigate the molecular mechanisms underlying the development of diseases and to …

Phospholipids are essential components of membrane lipid bilayers and serve as
precursors of multiple signaling molecules, so alterations in their homeostasis are …

Enabling technologies like Computational Chemistry, Bioinformatics, Combinatorial
Chemistry, Metabolomics, Proteomics (OMICS in general), etc., are expected to speed up …