Although patients with diabetes have 2 to 4 times increased risk of cardiovascular morbidity
and mortality than individuals without diabetes, recent studies indicate that a significant part …

This statement examines the cardiovascular complications of diabetes mellitus and
considers opportunities for their prevention. These complications include coronary heart …

Receptor for advanced glycation end products (RAGE) is a member of the immunoglobulin
superfamily of cell surface molecules and engages diverse ligands relevant to distinct …

Objectives: To critically analyze the literature linking microalbuminuria with total and
cardiovascular mortality and cardiovascular morbidity in non—insulin—dependent diabetes …

Hillege HL, Janssen WMT, Bak AAA, Diercks GFH, Grobbee DE, Crijns HJGM, van Gilst WH,
de Zeeuw D, de Jong PE for the PREVEND Study group (University of Groningen and …

Background Despite the numerous studies on the relation of albuminuria with increased risk
of all-cause mortality in type 2 diabetes mellitus, it remains uncertain whether …

Dysfunctional endothelium is associated with and, likely, predates clinical complications of
diabetes mellitus, by promoting increased vascular permeability and thrombogenicity …

Microalbuminuria (MA) is associated with adverse health outcomes in diabetic and
hypertensive adults. The prevalence and clinical significance of MA in nondiabetic …

Background and Purpose High blood pressure is the most important risk factor for stroke. It is
also known that diabetic patients are at increased risk of both hypertension and stroke. The …

Renoprotective benefits of RAS inhibition: From ACEI to angiotensin II antagonists. In
landmark clinical trials, pharmacological inhibition of the renin-angiotensin system (RAS) …