Glucose is the primary fuel to life on earth. Cellular uptake of glucose is a fundamental
process for metabolism, growth, and homeostasis. Three families of secondary glucose …

There are three families of glucose transporters in the human genome, SLC2, SLC5 and
SLC50. Here I review the structure and function of the SLC5 and SLC50 genes. The human …

Genetic factors modifying the blood metabolome have been investigated through genome-
wide association studies (GWAS) of common genetic variants and through exome …

The kidneys filter large amounts of glucose. To prevent the loss of this valuable fuel, the
tubular system of the kidney, particularly the proximal tubule, has been programmed to …

Sodium glucose transporters (SGLTs) belong to the mammalian solute carrier family SLC5.
This family includes 12 different members in human that mediate the transport of sugars …

Neutropenia and neutrophil dysfunction in glycogen storage disease type 1b (GSD1b) and
severe congenital neutropenia type 4 (SCN4), associated with deficiencies of the glucose-6 …

Glucose is a basic nutrient in most of the creatures; its transport through biological
membranes is an absolute requirement of life. This role is fulfilled by glucose transporters …

Abstract Purpose of Review The objective of this review is to provide up-to-date and
comprehensive discussion of tissue-specific fructose metabolism in the context of diabetes …

Background The metabolic syndrome (MS) is characterized by variable coexistence of
metabolic and pathophysiological alterations which are important risk factors for developing …

Glycogen storage disease type Ib (GSD1b) is due to a defect in the glucose-6-phosphate
transporter (G6PT) of the endoplasmic reticulum, which is encoded by the SLC37A4 gene …