[HTML][HTML] Polymeric micellar systems—a special emphasis on “smart” drug delivery

I Negut, B Bita - Pharmaceutics, 2023 - mdpi.com
Concurrent developments in anticancer nanotechnological treatments have been observed
as the burden of cancer increases every year. The 21st century has seen a transformation in …

Nanomaterial-based contrast agents

JC Hsu, Z Tang, OE Eremina, AM Sofias… - Nature Reviews …, 2023 - nature.com
Medical imaging, which empowers the detection of physiological and pathological
processes within living subjects, has a vital role in both preclinical and clinical diagnostics …

Vasculature organotropism in drug delivery

A Amruta, D Iannotta, SW Cheetham, T Lammers… - Advanced Drug Delivery …, 2023 - Elsevier
Over the past decades, there has been an exponential increase in the development of
preclinical and clinical nanodelivery systems, and recently, an accelerating demand to …

Design, development and clinical translation of CriPec®-based core-crosslinked polymeric micelles

CJF Rijcken, F De Lorenzi, I Biancacci… - Advanced drug delivery …, 2022 - Elsevier
Nanomedicines are used to improve the efficacy and safety of pharmacotherapeutic
interventions. Unraveling the biological behavior of nanomedicines, including their …

[HTML][HTML] Functionalized Polymeric Micelles for Targeted Cancer Therapy: Steps from Conceptualization to Clinical Trials

A Serras, C Faustino, L Pinheiro - Pharmaceutics, 2024 - mdpi.com
Cancer is still ranked among the top three causes of death in the 30-to 69-year-old age
group in most countries and carries considerable societal and macroeconomic costs that …

Photodynamically Tumor Vessel Destruction Amplified Tumor Targeting of Nanoparticles for Efficient Chemotherapy

P Yang, Y Xu, X Zhi, R Li, B Wang, R Liu, Z Dai… - ACS nano, 2024 - ACS Publications
Efficient tumor-targeted drug delivery is still a challenging and currently unbreakable
bottleneck in chemotherapy for tumors. Nanomedicines based on passive or active targeting …

[HTML][HTML] Advances in active targeting of ligand-directed polymeric nanomicelles via exploiting overexpressed cellular receptors for precise nanomedicine

MM Agwa, RE Marzouk, SA Sabra - RSC advances, 2024 - pubs.rsc.org
Many of the utilized drugs which already exist in the pharmaceutical sector are hydrophobic
in nature. These drugs are characterized by being poorly absorbed and difficult to formulate …

Ligand Conjugated Polymeric Micelles for Targeted Delivery of Drug Payloads in Cancer Therapy

SD Kaur, SK Singh, DK Chellappan, AA Aljabali… - Polymeric Micelles …, 2023 - Springer
Therapeutics can be delivered to specific areas in the body using ligand conjugated
polymeric micelles. Both passive and active targeting methods can be used to deliver …

[HTML][HTML] cRGD-platelet@ MnO/MSN@ PPARα/LXRα Nanoparticles Improve Atherosclerosis in Rats by Inhibiting Inflammation and Reducing Blood Lipid

Z Lv, Y Zhang, M Lu, Z Wang, X Nong, G Wen… - 2024 - benthamdirect.com
Objective Atherosclerosis (AS) is an inflammatory disease of arterial intima driven by lipids.
Liver X receptor alpha (LXRα) and peroxisome proliferator-activated receptor alpha …