Thyroid cancer (TC) is the eighth most frequently diagnosed cancer worldwide with a rising
incidence in the past 20 years. Surgery is the primary strategy of therapy for patients with …

The aim of the present study was to perform a systematic review of published studies to
provide a robust estimation of the use of procalcitonin (ProCT) as a diagnostic marker of …

Objective: To develop evidence-based recommendations for safe, effective, and appropriate
thyroidectomy. Background: Surgical management of thyroid disease has evolved …

Background Primary analysis of the double-blind, phase III Efficacy of XL184 (Cabozantinib)
in Advanced Medullary Thyroid Cancer (EXAM) trial demonstrated significant improvement …

Background The early detection of medullary thyroid carcinoma (MTC) can improve patient
prognosis, because histological stage and patient age at diagnosis are highly relevant …

Abstract The Bethesda System for Reporting Thyroid Cytology (TBSRTC) was proposed in
2007 at the National Cancer Institute Thyroid Fine Needle Aspiration State of the Art and …

Purpose The sensitivity of cytology after fine needle aspiration (FNA-cytology) in detecting
medullary thyroid carcinoma (MTC) is low. To overcome this problem, measuring calcitonin …

Advanced medullary thyroid cancers (MTCs) are now being treated with drugs that inhibit
receptor tyrosine kinases, many of which involved in angiogenesis. Response rates vary …

Fine-needle aspiration (FNA) is among the first diagnostic tools used in the evaluation of
thyroid nodules. It has the ability to triage patients with benign and malignant lesions, thus …

Generally, calcitonin (CT) values below the upper reference limit rule-out medullary thyroid
carcinoma (MTC) with very high accuracy. However, sparse cases of serum-calcitonin …