The dark side of foetal bovine serum in extracellular vesicle studies

O Urzì, R Olofsson Bagge… - Journal of extracellular …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) have been shown to be involved in cell‐cell communication and
to take part in both physiological and pathological processes. Thanks to their exclusive …

[HTML][HTML] A review of fetal bovine serum in the culture of mesenchymal stromal cells and potential alternatives for veterinary medicine

CR Pilgrim, KA McCahill, JG Rops… - Frontiers in Veterinary …, 2022 - frontiersin.org
Fetal bovine serum (FBS) remains widely used as a supplement in cell culture media used
in the isolation and expansion of mesenchymal stromal cells (MSC) despite longstanding …

Stromal cell therapy in cats with feline chronic gingivostomatitis: current perspectives and future direction

IL Rivas, M Soltero-Rivera… - Journal of feline …, 2023 - journals.sagepub.com
Feline chronic gingivostomatitis (FCGS) is a painful, immune-mediated, oral mucosal
inflammatory disease in cats. The etiology of FCGS remains unclear, with evidence pointing …

[HTML][HTML] Preparation technique affects recipient immune targeting of autologous mesenchymal stem cells

AL Rowland, ME Burns, GJ Levine… - Frontiers in veterinary …, 2021 - frontiersin.org
Fetal bovine serum (FBS) is used for MSC preparation in pre-clinical animal models and
veterinary applications, recently in US clinical trials, and for MSC products with current …

[HTML][HTML] Scalable production of equine platelet lysate for multipotent mesenchymal stromal cell culture

A Hagen, H Lehmann, S Aurich, N Bauer… - … in bioengineering and …, 2021 - frontiersin.org
Translation of multipotent mesenchymal stromal cell (MSC)-based therapies is advancing in
human and veterinary medicine. One critical issue is the in vitro culture of MSC before …

Human platelet lysate enhances proliferation but not chondrogenic differentiation of pediatric mesenchymal progenitors

OFW Gardner, N Agabalyan, B Weil, MHI Ali… - Cytotherapy, 2023 - Elsevier
Background aims Cell therapies have the potential to improve reconstructive procedures for
congenital craniofacial cartilage anomalies such as microtia. Adipose-derived stem cells …

[HTML][HTML] Secretome of adipose-derived stem cells cultured in platelet lysate improves migration and viability of keratinocytes

M Hermann, A Peddi, A Gerhards, R Schmid… - International Journal of …, 2023 - mdpi.com
Chronic wounds depict a silent epidemic challenging medical professionals worldwide.
Regenerative medicine uses adipose-derived stem cells (ADSC) in promising new …

[HTML][HTML] Enhanced osteochondral repair by leukocyte-depleted platelet-rich plasma in combination with adipose-derived mesenchymal stromal cells encapsulated in a …

T Iseki, BB Rothrauff, S Kihara, KJ Overholt… - Stem Cell Research & …, 2024 - Springer
Introduction Intra-articular injection of adipose-derived mesenchymal stromal cells (ASCs)
and/or platelet-rich plasma (PRP) have been reported to independently and synergistically …

Effects of continuous passage on the immunomodulatory properties of equine bone marrow-derived mesenchymal stem cells in vitro

SS Connard, RL Linardi, KM Even, AK Berglund… - Veterinary immunology …, 2021 - Elsevier
Background The immunomodulatory properties of mesenchymal stem cells (MSCs) have
been studied extensively due to their increasing clinical application for tissue regeneration …

[HTML][HTML] Comparing the immunomodulatory properties of equine BM-MSCs culture expanded in autologous platelet lysate, pooled platelet lysate, equine serum and …

KM Even, AM Gaesser, SA Ciamillo… - Frontiers in Veterinary …, 2022 - frontiersin.org
Joint injury often leads to cartilage damage and posttraumatic inflammation, which drives
continued extracellular matrix degradation culminating in osteoarthritis. Mesenchymal stem …