Altered nucleus accumbens functional connectivity precedes apathy in Parkinson's disease

LA Morris, SJ Harrison, TR Melzer, JC Dalrymple-Alford… - Brain, 2023 - academic.oup.com
Work in animal and human neuroscience has identified neural regions forming a network
involved in the production of motivated, goal-directed behaviour. In particular, the nucleus …

Dimensions of apathy in Parkinson's disease

N Thompson, M MacAskill, M Pascoe… - Brain and …, 2023 - Wiley Online Library
Introduction Apathy is one of the most common neuropsychiatric manifestations in
Parkinson's disease (PD). Recent proposals consider apathy as a multidimensional …

Early‐phase amyloid PET reproduces metabolic signatures of cognitive decline in Parkinson's disease

WWT Aye, MR Stark, KL Horne… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION Recent work suggests that amyloid beta (Aβ) positron emission
tomography (PET) tracer uptake shortly after injection (“early phase”) reflects brain …

Cross-Sectional and Longitudinal Association of Clinical and Neurocognitive Factors With Apathy in Patients With Parkinson Disease

C Le Heron, KL Horne, MR MacAskill, L Livingstone… - Neurology, 2024 - AAN Enterprises
Background and Objectives A robust understanding of the natural history of apathy in
Parkinson disease (PD) is foundational for developing effective clinical management tools …

[HTML][HTML] What have we learned from longitudinal studies in Aotearoa New Zealand?

AJ Osborne, JM Broadbent, SMB Morton… - Journal of the Royal …, 2023 - Taylor & Francis
This second part of this Special Issue includes six papers. Edwards et al discuss how
longitudinal research grounded in Māori concepts of lifecourse is urgently needed in …