One of the main causes of acute respiratory distress syndrome in coronavirus disease 2019
(COVID-19) is cytokine storm, although the exact cause is still unknown. Umbilical cord …

Cytokine storm, known as an exaggerated hyperactive immune response characterized by
elevated release of cytokines, has been described as a feature associated with life …

In late 2019, a novel betacoronavirus, later termed severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), was discovered in patients with an unknown respiratory …

COVID-19 has been affecting the world unprecedentedly and will remain widely prevalent
due to its elusive pathophysiological mechanism and the continuous emergence of new …

Vagus nerve stimulation (VNS) is considered a potential method for anti-inflammation due to
the involvement of the VN in the cholinergic anti-inflammatory pathway (CAP) formation of a …

Serial measurement of a large panel of protein biomarkers near the bedside could provide a
promising pathway to transform the critical care of acutely ill patients. However, attaining the …

The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes
coronavirus disease 2019 (COVID-19) through excessive end organ inflammation. Despite …

Digital protein assays have great potential to advance immunodiagnostics because of their
single-molecule sensitivity, high precision, and robust measurements. However, translating …

OBJECTIVES: To evaluate safety and clinical outcomes of extracorporeal
immunomodulation treatment with a selective cytopheretic device (SCD) in COVID-19 ICU …

Introduction Critically ill children with acute kidney injury (AKI) requiring continuous kidney
replacement therapy (CKRT) are at increased risk of death. The selective cytopheretic …