Bax, Bcl-2, and Bax/Bcl-2 as prognostic markers in acute myeloid leukemia: are we ready for Bcl-2-directed therapy?

B Kulsoom, TS Shamsi, NA Afsar… - Cancer management …, 2018 - Taylor & Francis
Purpose Many anticancer drugs induce apoptosis in malignant cells, and resistance to
apoptosis could lead to suboptimal or no therapeutic benefit. Two cytoplasmic proteins, B …

[PDF][PDF] Clinical presentation of acute myeloid leukaemia—A decade-long institutional follow-up

B Kulsoom, TS Shamsi, N Ahmed, SN Hasnain - changes, 2017 - researchgate.net
Objective: To analyse a decade-long pattern of clinical presentation of acute myeloid
leukaemia patients and compare it with contemporary data. Methods: The retrospective …

[HTML][HTML] A study to determine the clinical, hematological, cytogenetic, and molecular profile in CML patient in and around Eastern UP, India

S Kumar, VK Gupta, A Bharti, LP Meena… - Journal of family …, 2019 - journals.lww.com
Objectives: A study to determine the clinical, hematological, cytogenetic, and molecular
profile in chronic myeloid leukemia (CML) patient in and around Eastern UP, India. Materials …

Systematic review of the burden and treatment patterns of adult and adolescent acute lymphoblastic leukemia in India: comprehending the challenges in an emerging …

VS Radhakrishnan, N Agrawal, B Bagal… - … Lymphoma Myeloma and …, 2021 - Elsevier
Background In the present systematic literature review, we sought to describe the burden
and treatment practices of adult acute lymphoblastic leukemia (ALL) in India, which reflect …

[HTML][HTML] Immunophenotypic aberrancies in acute leukemia: a tertiary care centre experience

M Gupta, L Monga, D Mehrotra, S Chhabra… - Oman Medical …, 2021 - ncbi.nlm.nih.gov
Objectives Acute leukemias (AL) are a heterogeneous group of hematological malignancies
with the presence of 20% or more blasts in the peripheral blood or bone marrow. Malignant …

[HTML][HTML] The frequency of aberrant CD7 antigen expression in acute myeloid leukaemia patients

H Raza, M Fatima, T Noor, S Umer, A Imran, NA Malik - Cureus, 2022 - ncbi.nlm.nih.gov
Background Aberrant phenotype expression in acute myeloid leukemia (AML) may be due
to genetic defects and is associated with a poor prognosis. CD7 is the first T-cell-associated …

[HTML][HTML] Clinical and Laboratory Manifestation of Children with Acute Lymphoblastic Leukemia as an Assessment of Severity: A Study in Dr. Hasan Sadikin General …

YK Angkasa, N Suryawan… - Althea Medical Journal, 2019 - journal.fk.unpad.ac.id
Background: Acute lymphoblastic leukemia (ALL) is a disease caused by a mutation of
lymphoid progenitor cells in bone marrow, that induces uncontrolled lymphoid cell …

[PDF][PDF] Cytogenetic Analysis of Chronic Myeloid Leukemia in an Eastern Indian Population

A Kumar, V Tilak, A Ali - Int J Clin Med Edu Res, 2023 - academia.edu
Chronic myeloid leukaemia (CML) is a common translocation known as BCR-ABL1, also
referred to as the Philadelphia chromosome, that affects the primitive hematopoietic stem …

[PDF][PDF] Silencing the PIK3CA Gene Enhances the Sensitivity of Childhood Leukemia Cells to Chemotherapy Drugs by Suppressing the Phosphorylation of Akt

X Liang, X Xin, D Qi, C Fu, M Ding - Yonsei Medical Journal, 2019 - synapse.koreamed.org
Purpose This study aimed to investigate the effects of PIK3CA on the sensitivity of acute B
lymphocytic leukemia cells (Nalm-6 cells) to chemotherapy drugs. Materials and Methods …

[HTML][HTML] Cytokines profiling as prognostic markers in newly diagnosed acute myeloid leukemia

HS Ahmed, NT Tahir, FA Obed - Iraqi Journal of Hematology, 2017 - journals.lww.com
BACKGROUND: Acute myeloid leukemia (AML) is a common acute leukemia in adult.
Recent studies have shown that cytokine systems influence leukemic cell biology and …