Cytokines play a central role in the pathophysiology of autoimmune and inflammatory
diseases. Several cytokines signal through the JAK-STAT pathway, which is now recognized …

Melanin, the compound primarily responsible in humans for hair, eye and skin pigmentation,
is produced by melanocytes through a complicated process called melanogenesis that is …

The skin serves as a physical barrier and an immunological interface that protects the body
from the external environment,–. Aberrant activation of immune cells can induce common …

Extracellular tissue fluids are interesting biomatrices that have recently attracted scientists'
interest. Many significant biomarkers for localized external organ diseases have been …

Paraneoplastic pemphigus is a rare autoimmune skin disease that is always associated with
a neoplasm. Usually, oral, skin, and mucosal lesions are the earliest manifestations shown …

Background Vitiligo is an acquired depigmenting skin disease which is often accompanied
by mental distress. There are numerous studies dedicated to local and global prevalence of …

With the public's growing interest in skin whitening, lightening ingredients only used under
dermatological supervision until recently, are more and more frequently incorporated into …

Vitiligo is a multifactorial disease characterized by the loss of skin pigment, which results in
achromic macules and patches. There are currently several medical treatments available …

Inositol-requiring transmembrane kinase/endoribonuclease 1α (IRE1α) is the most
prominent and evolutionarily conserved endoplasmic reticulum (ER) membrane protein …

Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe
drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are …