Growth hormone, insulin-like growth factors, and the skeleton

A Giustina, G Mazziotti, E Canalis - Endocrine reviews, 2008 - academic.oup.com
Abstract GH and IGF-I are important regulators of bone homeostasis and are central to the
achievement of normal longitudinal bone growth and bone mass. Although GH may act …

Serum levels of insulin-like growth factor I and its binding proteins in health and disease

A Juul - Growth hormone & IGF research, 2003 - Elsevier
Postnatal growth and development of the human body and its specific organs are regulated
by a complex network of local and systemic factors which is poorly understood. This review …

Role of insulin‐like growth factors and their binding proteins in growth control and carcinogenesis

A Grimberg, P Cohen - Journal of cellular physiology, 2000 - Wiley Online Library
Interest in the role of the insulin‐like growth factor (IGF) axis in growth control and
carcinogenesis has recently been increased by the finding of elevated serum insulin‐like …

Free insulin-like growth factors–measurements and relationships to growth hormone secretion and glucose homeostasis

J Frystyk - Growth Hormone & IGF Research, 2004 - Elsevier
IGF-I is a multipotent growth factor with important actions on normal tissue growth and
regeneration. In addition, IGF-I has been suggested to have beneficial effects on glucose …

Anorexia nervosa in female adolescents: endocrine and bone mineral density disturbances

MT Munoz, J Argente - European Journal of Endocrinology, 2002 - academic.oup.com
Anorexia nervosa (AN) is a chronic childhood psychiatric illness that involves a reduction in
caloric intake, loss of weight and amenorrhea, either primary or secondary. The diagnostic …

Mechanisms in endocrinology: anorexia nervosa and endocrinology: a clinical update

RK Støving - European journal of endocrinology, 2019 - academic.oup.com
Anorexia nervosa is a syndrome, that is collections of symptoms, which is not defined by its
etiology. The severe cases are intractable. The syndrome is associated with multiple …

Insulin-like growth factor-I (IGF-I) and clinical nutrition

C Livingstone - Clinical science, 2013 - portlandpress.com
IGF-I (insulin-like growth factor-I) is a peptide hormone, produced predominantly by the liver
in response to pituitary GH (growth hormone), which is involved in a wide variety of …

Jointly amplified basal and pulsatile growth hormone (GH) secretion and increased process irregularity in women with anorexia nervosa: indirect evidence for …

RK Støving, JD Veldhuis, A Flyvbjerg… - The Journal of …, 1999 - academic.oup.com
Anorexia nervosa (AN) is associated with multiple endocrine alterations. In the majority of
AN patients, basal and GHRH-stimulated serum GH levels are increased. The metabolic …

Insulin-like growth factor 1 (IGF-1), a nutritional marker in patients with eating disorders

L Caregaro, A Favaro, P Santonastaso, F Alberino… - Clinical Nutrition, 2001 - Elsevier
Background and aims: Though low levels of insulin-like growth factor-1 (IGF-1) have been
repeatedly reported in patients with eating disorders, the nutritional significance of IGF-1 has …

The regulation of reproductive neuroendocrine function by insulin and insulin-like growth factor-1 (IGF-1)

A Wolfe, S Divall, S Wu - Frontiers in neuroendocrinology, 2014 - Elsevier
The mammalian reproductive hormone axis regulates gonadal steroid hormone levels and
gonadal function essential for reproduction. The neuroendocrine control of the axis …