Virally induced liver cancer usually evolves over long periods of time in the context of a
strongly oxidative microenvironment, characterized by chronic liver inflammation and …

With respect to their genome and their structure, the human hepatitis B virus (HBV) and
hepatitis C virus (HCV) are complete different viruses. However, both viruses can cause an …

The nuclear factor erythroid 2 related factor 2 (Nrf2) is a major regulator of intracellular
inducible defense systems against harmful endogenous and exogenous substances in the …

Mitophagy is a selective form of autophagy, targeting damaged mitochondria for lysosomal
degradation. Although HCV infection has been shown to induce mitophagy, the precise …

Herpes simplex virus-2 (HSV-2) is a leading cause of sexually transmitted infections for
which no effective vaccines or prophylactic treatment currently exist. Nuclear factor erythroid …

In humans, acute and chronic respiratory infections caused by viruses are associated with
considerable morbidity and mortality. Respiratory viruses infect airway epithelial cells and …

Eukaryotic cells adopt highly tuned stress response physiology under threats of exogenous
stressors including viruses to maintain cellular homeostasis. Not surprisingly, avoidance of …

Background: Infection with tick-borne encephalitis virus (TBEV) causes pathological
changes in the central nervous system. However, the possible redox alterations in the …

Chronic infection with hepatitis C virus (HCV) induces liver fibrosis and cancer. In particular
metabolic alterations and associated oxidative stress induced by the virus play a key role in …

Chronic viral hepatitis is a main cause of liver disease and hepatocellular carcinoma. There
are striking similarities in the pathological impact of hepatitis B, C, and D, although these …