Epilepsy, a neurological disease characterized by recurrent seizures, is highly
heterogeneous in nature. Based on the prevalence, epilepsy is classified into two types …

Hypertension is considered a major public health issue due to its high prevalence and
subsequent risk of cardiovascular and kidney diseases. Thus, the search for new …

In recent decades, medical research has been primarily focused on the inherited aspect of
cancers, despite the reality that only 5–10% of tumours discovered are derived from genetic …

BACKGROUND: Disease-causing mutations in CACNA1D gene occur in aldosterone-
producing adenomas and familial hyperaldosteronism. We determined whether single …

Blood vasculature plays an essential role in transporting nanomaterials in vivo. However,
the interaction between vascular endothelial cells (VECs) and nanomaterials lacked deep …

Cardiac excitation–contraction coupling is initiated with the influx of Ca2+ ions across the
plasma membrane through voltage-gated L-type calcium channels. This process is tightly …

The CACNA1C gene encodes the alpha-1c subunit of the Ca v 1.2 calcium channel, a
regulator of neuronal calcium influx involved in neurotransmitter release and synaptic …

Abstract Background Human Ca V 1.2 (hCav1. 2), a calcium selective voltage-gated
channel, plays important roles in normal cardiac and neuronal functions. Calcium influx and …

Aims From the synthesis of 43 lipophilic dihydropyridines, the aim of this study was to verify
whether the new dihydropyridines have calcium channel affinity using coupling studies and …

Pendahuluan: Infeksi cacing merupakan permasalahan kesehatan di Indonesia.
Tatalaksana helminthiasis selama ini menggunakan anti helminth seperti pirantel pamoat …