Electrochemical transformations catalyzed by cytochrome P450s and peroxidases

N Kumar, J He, JF Rusling - Chemical Society Reviews, 2023 - pubs.rsc.org
Cytochrome P450s (Cyt P450s) and peroxidases are enzymes featuring iron heme cofactors
that have wide applicability as biocatalysts in chemical syntheses. Cyt P450s are a family of …

[HTML][HTML] Design and biocatalytic applications of genetically fused multifunctional enzymes

DT Monterrey, I Ayuso-Fernández, I Oroz-Guinea… - Biotechnology …, 2022 - Elsevier
Fusion proteins, understood as those created by joining two or more genes that originally
encoded independent proteins, have numerous applications in biotechnology, from …

Engineering enzyme properties for improved biocatalytic processes in batch and continuous flow

RA Rocha, RE Speight, C Scott - Organic Process Research & …, 2022 - ACS Publications
The widespread adoption of biocatalysis by industry to perform highly selective chemical
syntheses has been made possible only by the development of highly effective methods in …

A short review on catalyst, feedstock, modernised process, current state and challenges on biodiesel production

AG Alsultan, N Asikin-Mijan, Z Ibrahim, R Yunus… - Catalysts, 2021 - mdpi.com
Biodiesel, comprising mono alkyl fatty acid esters or methyl ethyl esters, is an encouraging
option to fossil fuels or diesel produced from petroleum; it has comparable characteristics …

A selective and atom-economic rearrangement of uridine by cascade biocatalysis for production of pseudouridine

M Pfeiffer, A Ribar, B Nidetzky - Nature Communications, 2023 - nature.com
As a crucial factor of their therapeutic efficacy, the currently marketed mRNA vaccines
feature uniform substitution of uridine (U) by the corresponding C-nucleoside, pseudouridine …

Multienzymatic cascades and nanomaterial scaffolding—a potential way forward for the efficient biosynthesis of novel chemical products

SL Hooe, AD Smith, SN Dean, JC Breger… - Advanced …, 2024 - Wiley Online Library
Synthetic biology is touted as the next industrial revolution as it promises access to greener
biocatalytic syntheses to replace many industrial organic chemistries. Here, it is shown to …

Cascades of evolved enzymes for the synthesis of complex molecules

K Rosenthal, UT Bornscheuer… - Angewandte Chemie …, 2022 - Wiley Online Library
Thanks to advances in enzyme discovery and protein engineering combined with the
development of enzymatic multistep reaction cascades, new efficient routes for drug …

Voltage-controlled divergent cascade of electrochemical reactions for characterization of lipids at multiple isomer levels using mass spectrometry

S Tang, X Chen, Y Ke, F Wang, X Yan - Analytical chemistry, 2022 - ACS Publications
Cascading divergent reactions in a single system is highly desirable for their intrinsic
efficiency and potential to achieve multilevel structural characterization of complex …

Cell-free enzyme cascades—application and transition from development to industrial implementation

M Teshima, VP Willers, V Sieber - Current Opinion in Biotechnology, 2023 - Elsevier
Highlights•State-of-the-art in vitro enzyme cascades to assimilate CO 2-derived C1
compounds.•Current transitioning state of the biomass-based production of commodity …

Recent advances in biocatalysis for drug synthesis

A Kinner, P Nerke, R Siedentop, T Steinmetz… - Biomedicines, 2022 - mdpi.com
Biocatalysis is constantly providing novel options for the synthesis of active pharmaceutical
ingredients (APIs). In addition to drug development and manufacturing, biocatalysis also …