[HTML][HTML] In silico vaccine design: A tutorial in immunoinformatics

DD Martinelli - Healthcare Analytics, 2022 - Elsevier
Immunoinformatics, as a discipline, concerns the application of computational systems to
study the immune system. Recently, the principles of reverse vaccinology have united with …

Linear B-cell epitope prediction for in silico vaccine design: A performance review of methods available via command-line interface

KA Galanis, KC Nastou, NC Papandreou… - International journal of …, 2021 - mdpi.com
Linear B-cell epitope prediction research has received a steadily growing interest ever since
the first method was developed in 1981. B-cell epitope identification with the help of an …

Decision tree based ensemble machine learning model for the prediction of Zika virus T-cell epitopes as potential vaccine candidates

SNH Bukhari, J Webber, A Mehbodniya - Scientific Reports, 2022 - nature.com
Zika fever is an infectious disease caused by the Zika virus (ZIKV). The disease is claiming
millions of lives worldwide, primarily in developing countries. In addition to vector control …

Contriving multi-epitope subunit of vaccine for COVID-19: immunoinformatics approaches

R Dong, Z Chu, F Yu, Y Zha - Frontiers in immunology, 2020 - frontiersin.org
COVID-19 has recently become the most serious threat to public health, and its prevalence
has been increasing at an alarming rate. The incubation period for the virus is~ 1–14 days …

In silico design and immunoinformatics analysis of a universal multi-epitope vaccine against monkeypox virus

S Sanami, S Nazarian, S Ahmad, E Raeisi… - Plos one, 2023 - journals.plos.org
Monkeypox virus (MPXV) outbreaks have been reported in various countries worldwide;
however, there is no specific vaccine against MPXV. In this study, therefore, we employed …

Designing a multi-epitope peptide based vaccine against SARS-CoV-2

A Singh, M Thakur, LK Sharma, K Chandra - Scientific reports, 2020 - nature.com
COVID-19 pandemic has resulted in 16,114,449 cases with 646,641 deaths from the 217
countries, or territories as on July 27th 2020. Due to multifaceted issues and challenges in …

In-silico design of a multivalent epitope-based vaccine against Candida auris

N Akhtar, A Joshi, V Kaushik, M Kumar… - Microbial …, 2021 - Elsevier
Candida auris is a rapidly emerging human pathogenic fungus with a high mortality rate.
Recent report suggests that the new clinical isolates are showing resistance to the major …

[Retracted] Machine Learning‐Based Ensemble Model for Zika Virus T‐Cell Epitope Prediction

SNH Bukhari, A Jain, E Haq, MA Khder… - Journal of …, 2021 - Wiley Online Library
Zika virus (ZIKV), the causative agent of Zika fever in humans, is an RNA virus that belongs
to the genus Flavivirus. Currently, there is no approved vaccine for clinical use to combat the …

Immunoinformatics guided rational design of a next generation multi epitope based peptide (MEBP) vaccine by exploring Zika virus proteome

F Shahid, UA Ashfaq, A Javaid, H Khalid - Infection, genetics and evolution, 2020 - Elsevier
Zika virus (ZIKV) is an RNA virus that has spread through mosquito sting. Currently, no
vaccine and antiviral medication available so far against ZIKV. Therefore, it has fostered a …

An overview of in silico vaccine design against different pathogens and cancer

K Kardani, A Bolhassani, A Namvar - Expert Review of Vaccines, 2020 - Taylor & Francis
Introduction Due to overcome the hardness of the vaccine design, computational
vaccinology is emerging widely. Prediction of T cell and B cell epitopes, antigen processing …