Central pattern generators in the brainstem and spinal cord: an overview of basic principles, similarities and differences

I Steuer, PA Guertin - Reviews in the Neurosciences, 2019 - degruyter.com
Central pattern generators (CPGs) are generally defined as networks of neurons capable of
enabling the production of central commands, specifically controlling stereotyped, rhythmic …

Three-dimensional virtual refocusing of fluorescence microscopy images using deep learning

Y Wu, Y Rivenson, H Wang, Y Luo, E Ben-David… - Nature …, 2019 - nature.com
We demonstrate that a deep neural network can be trained to virtually refocus a two-
dimensional fluorescence image onto user-defined three-dimensional (3D) surfaces within …

Whole-organism behavioral profiling reveals a role for dopamine in state-dependent motor program coupling in C. elegans

N Cermak, SK Yu, R Clark, YC Huang, SN Baskoylu… - Elife, 2020 - elifesciences.org
Animal behaviors are commonly organized into long-lasting states that coordinately impact
the generation of diverse motor outputs such as feeding, locomotion, and grooming …

The head mesodermal cell couples FMRFamide neuropeptide signaling with rhythmic muscle contraction in C. elegans

U Choi, M Hu, Q Zhang, D Sieburth - Nature Communications, 2023 - nature.com
FMRFamides are evolutionarily conserved neuropeptides that play critical roles in behavior,
energy balance, and reproduction. Here, we show that FMRFamide signaling from the …

A single neuron in C. elegans orchestrates multiple motor outputs through parallel modes of transmission

YC Huang, J Luo, W Huang, CM Baker, MA Gomes… - Current Biology, 2023 - cell.com
Animals generate a wide range of highly coordinated motor outputs, which allows them to
execute purposeful behaviors. Individual neurons in the circuits that generate behaviors …

C. elegans: a prominent platform for modeling and drug screening in neurological disorders

S Romussi, S Giunti, N Andersen… - Expert Opinion on Drug …, 2024 - Taylor & Francis
Introduction Human neurodevelopmental and neurodegenerative diseases (NDevDs and
NDegDs, respectively) encompass a broad spectrum of disorders affecting the nervous …

Ratiometric calcium imaging of individual neurons in behaving Caenorhabditis elegans

B Ravi, LM Nassar, RJ Kopchock III… - Journal of …, 2018 - pmc.ncbi.nlm.nih.gov
It has become increasingly clear that neural circuit activity in behaving animals differs
substantially from that seen in anesthetized or immobilized animals. Highly sensitive …

Caenorhabditis elegans Male Copulation Circuitry Incorporates Sex-Shared Defecation Components To Promote Intromission and Sperm Transfer

B LeBoeuf, LR Garcia - G3: Genes, Genomes, Genetics, 2017 - academic.oup.com
Sexual dimorphism can be achieved using a variety of mechanisms, including sex-specific
circuits and sex-specific function of shared circuits, though how these work together to …

Interneurons Regulate Locomotion Quiescence via Cyclic Adenosine Monophosphate Signaling During Stress-Induced Sleep in Caenorhabditis elegans

A Cianciulli, L Yoslov, K Buscemi, N Sullivan… - Genetics, 2019 - academic.oup.com
Sleep is evolutionarily conserved, thus studying simple invertebrates such as
Caenorhabditis elegans can provide mechanistic insight into sleep with single cell …

Glia in Invertebrate Models: Insights from Caenorhabditis elegans

MD Purice, LJ Severs, A Singhvi - Astrocyte-Neuron Interactions in Health …, 2024 - Springer
Glial cells modulate brain development, function, and health across all bilaterian animals,
and studies in the past two decades have made rapid strides to uncover the underlying …