Abstract 'Reactive oxygen species'(ROS) is a generic term that defines a wide variety of
oxidant molecules with vastly different properties and biological functions that range from …

Protein glycosylation involves the co-translational or post-translational addition of glycans to
proteins and is a crucial protein modification in health and disease. The aim of …

Many industrial chemicals that are produced from fossil resources could be manufactured
more sustainably through fermentation. Here we describe the development of a carbon …

A critical step in proteomics analysis is the optimal extraction and processing of protein
material to ensure the highest sensitivity in downstream detection. Achieving this requires a …

State-of-the-art proteomics-grade mass spectrometers can measure peptide precursors and
their fragments with ppm mass accuracy at sequencing speeds of tens of peptides per …

We evaluate the quantitative performance of the newly released Asymmetric Track Lossless
(Astral) analyzer. Using data-independent acquisition, the Thermo Scientific Orbitrap Astral …

Liver fibrosis is a strong predictor of long-term mortality in individuals with metabolic-
associated fatty liver disease; yet, the mechanisms underlying the progression from the …

Achieving sufficient coverage of regulatory phosphorylation sites by mass spectrometry (MS)-
based phosphoproteomics for signaling pathway reconstitution is challenging, especially …

The prevalence of Parkinson's disease (PD) is increasing but the development of novel
treatment strategies and therapeutics altering the course of the disease would benefit from …

Species determination based on genetic evidence is an indispensable tool in archaeology,
forensics, ecology, and food authentication. Most available analytical approaches involve …