Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

Clathrin-mediated endocytosis is the endocytic portal into cells through which cargo is
packaged into vesicles with the aid of a clathrin coat. It is fundamental to neurotransmission …

Endocytosis is a fundamental process in which eukaryotic cells internalise molecules and
macromolecules via deformation of the membrane and generation of membrane-bound …

Candida albicans is a common fungal pathogen of humans that colonizes the skin and
mucosal surfaces of most healthy individuals. Until recently, little was known about the …

The interaction between Candida albicans and its host cells is characterized by a complex
interplay between the expression of fungal virulence factors, which results in adherence …

Candida species are the most common causes of fungal infection. Approximately 90% of
infections are caused by five species: Candida albicans, Candida glabrata, Candida …

The ability to switch between yeast and hyphal growth forms (dimorphism) is one of the most
discussed and best investigated virulence attributes of the human pathogenic fungus …

Candida albicans is part of the normal human flora, and it grows on mucosal surfaces in
healthy individuals. In susceptible hosts, this organism can cause both mucosal and …

Candida albicans interactions with epithelial cells are critical for commensal growth, fungal
pathogenicity and host defence. This review will outline our current understanding of C …

Fungal infections are an increasing threat to global public health. There are more than six
million fungal species worldwide, but less than 1% are known to infect humans. Most of …