Plague is a vector-borne disease caused by Yersinia pestis. Transmitted by fleas from
rodent reservoirs, Y. pestis emerged< 6000 years ago from an enteric bacterial ancestor …

In recent years, aquaculture has attained a major economic revolution, however, infectious
diseases of bacterial, viral, mycotic and parasitic origin are the most significant restrictive …

The current human whole-cell vaccine is ineffective against pneumonic plague caused by
typical F1 capsule positive (F1+) strains of Yersinia pestis. The authors found this vaccine to …

The type III secretion machinery of Gram‐negative bacteria, also known as the injectisome
or needle complex, is composed of a basal body spanning both bacterial membranes and …

The purified recombinant V antigen from Yersinia pestis, expressed in Escherichia coli and
adsorbed to aluminum hydroxide, an adjuvant approved for human use, was used to …

Yersinia pestis is the etiological agent of bubonic and pneumonic plague, diseases which
have caused over 200 milllion human deaths in the past. Plague still occurs throughout the …

The human immune response to a new recombinant plague vaccine, comprising
recombinant F1 (rF1) and rV antigens, has been assessed during a phase 1 safety and …

Inhalation of Yersinia pestis bacilli causes pneumonic plague, a rapidly progressing and
exceptionally virulent disease. Extensively antibiotic-resistant Y. pestis strains exist and we …

Bacillus anthracis and Yersinia pestis, the causative agents of anthrax and plague,
respectively, are two of the deadliest pathogenic bacteria that have been used as biological …

Pulmonary infection with the bacterium Yersinia pestis causes pneumonic plague, an often-
fatal disease for which no vaccine is presently available. Antibody-mediated humoral …