Therapeutic effect and safety of stem cell therapy for chronic liver disease: a systematic review and meta-analysis of randomized controlled trials

GP Zhou, YZ Jiang, LY Sun, ZJ Zhu - Stem Cell Research & Therapy, 2020 - Springer
Background Stem cell therapy is becoming an emerging therapeutic option for chronic liver
disease (CLD). However, whether stem cell therapy is more effective than conventional …

Preclinical-to-clinical innovations in stem cell therapies for liver regeneration

S Chawla, A Das - Current Research in Translational Medicine, 2023 - Elsevier
Acute and chronic liver diseases are the major cause of high morbidity and mortality
globally. Liver transplantation is a widely used therapeutic option for liver failure. However …

BM-MSCs overexpressing the Numb enhance the therapeutic effect on cholestatic liver fibrosis by inhibiting the ductular reaction

Y Xu, W Xu, X Zhang, D Wang, X Zheng, W Liu… - Stem Cell Research & …, 2023 - Springer
Background Cholestatic liver fibrosis (CLF) is caused by inflammatory destruction of the
intrahepatic bile duct and abnormal proliferation of the small bile duct after cholestasis …

Liver regeneration by hematopoietic stem cells: have we reached the end of the road?

EK Siapati, MG Roubelakis, G Vassilopoulos - Cells, 2022 - mdpi.com
The liver is the organ with the highest regenerative capacity in the human body. However,
various insults, including viral infections, alcohol or drug abuse, and metabolic overload …

Stem cell therapy for hepatocellular carcinoma and end-stage liver disease

MS Abdellateif, ARN Zekri - Journal of the Egyptian National Cancer …, 2023 - Springer
Hepatocellular carcinoma (HCC) is a major health problem worldwide, especially for
patients who are suffering from end-stage liver disease (ESLD). The ESLD is considered a …

Cell and cell-derivative-based therapy for liver diseases: current approaches and future promises

E Zahmatkesh, N Khoshdel Rad… - Expert Review of …, 2023 - Taylor & Francis
Introduction According to the recent updates from World Health Organization, liver diseases
are the 12th most common cause of mortality. Currently, orthotopic liver transplantation …

Effectiveness of cell-and colony stimulating factor-based therapy for liver cirrhosis: a network meta-analysis of randomized controlled trials

X Sun, S Guo - Cytotherapy, 2022 - Elsevier
Background aims Cirrhosis is the 11th leading cause of death worldwide. Because of the
limitations of liver transplantation, cell-and granulocyte colony-stimulating factor (G-CSF) …

Stem Cell Therapy as a Potential Treatment of Non-Alcoholic Steatohepatitis-Related End-Stage Liver Disease: A Narrative Review

A Mahmoudi, P Meidany, W Almahmeed… - Current Stem Cell …, 2024 - Springer
Stem cell therapy remains in its infancy though may have a major role in the future of
regenerative medicine and in particular for the treatment of NAFLD and NASH, either alone …

骨髓巨噬细胞M2 亚型共培养后的骨髓间充质干细胞移植治疗肝硬化大鼠模型的效果分析.

郑欣瑞, 许燕楠, 王丹阳, 邢飞飞… - Journal of Clinical …, 2024 - search.ebscohost.com
目的探讨骨髓巨噬细胞M2 亚型(M2-BMDM) 共培养后的骨髓间充质干细胞(BMSC M2)
移植对四氯化碳/2-乙酰氨基芴(CCl4/2-AAF) 诱导肝硬化大鼠模型进展的影响 …

[PDF][PDF] Comparative Efficacy of Stem Cells on Chronic Decompensated Cirrhosis: A Network Meta-analysis

D Jin, S Jin, P Gao, B Guo, G Li… - Clinical Medicine, 2024 - article.clinmedfront.com
Currently, liver transplantation is the best way to improve the survival rate of decompensated
cirrhosis, but its application is limited due to the shortage of donors and high cost. In the …