Oligodendrocytes generate multiple layers of myelin membrane around axons of the central
nervous system to enable fast and efficient nerve conduction. Until recently, saltatory nerve …

Carbohydrates are essential mediators of many processes in health and disease. They
regulate self-/non-self-discrimination, are key elements of cellular communication, cancer …

Human betacoronaviruses OC43 and HKU1 are endemic respiratory pathogens and, while
related, originated from independent zoonotic introductions. OC43 is in fact a host-range …

(MS) and MS-driven proteomics have continued to develop as the premier tools for
characterizing proteome composition, structure, and function. 2 The new era of proteomics …

The propagation of electrical impulses along axons is highly accelerated by the myelin
sheath and produces saltating or" jumping" action potentials across internodes, from one …

The biological functions of tryptophan C-mannosylation are poorly understood, in part, due
to a dearth of methods for preparing pure glycopeptides and glycoproteins with this …

Abstract Knowledge of molecular weight, oligomeric states, and quaternary arrangements of
proteins in solution is fundamental for understanding their molecular functions and activities …

CD22 maintains a baseline level of B-cell inhibition to keep humoral immunity in check. As a
B-cell-restricted antigen, CD22 is targeted in therapies against dysregulated B cells that …

Ubiquitous occurrence in Nature, abundant presence at strategically important places such
as the cell surface and dynamic shifts in their profile by diverse molecular switches qualifies …

C-linked glycosylation is essential for the trafficking, folding and function of secretory and
transmembrane proteins involved in cellular communication processes. The tryptophan C …