New generation QuIC assays for prion seeding activity
CD Orru, JM Wilham, S Vascellari, AG Hughson… - Prion, 2012 - Taylor & Francis
The ability of abnormal TSE-associated forms of PrP to seed the formation of amyloid fibrils
from recombinant PrPSen has served as the basis for several relatively rapid and highly …
from recombinant PrPSen has served as the basis for several relatively rapid and highly …
Scrapie, CWD, and transmissible mink encephalopathy
CK Mathiason - Progress in molecular biology and translational …, 2017 - Elsevier
Transmissible spongiform encephalopathies (TSEs), or prions, are neurodegenerative
diseases that affect a variety of animal species, including humans. Cruetzfeldt–Jakob …
diseases that affect a variety of animal species, including humans. Cruetzfeldt–Jakob …
Classical and atypical scrapie in sheep and goats
C Fast, MH Groschup - Prions and Diseases: Volume 2, Animals, Humans …, 2013 - Springer
Scrapie is a naturally occuring transmissible spongiform encephalopathy (TSE) in sheep,
goat and mufflons almost world-wide and is known for about 250 years. It is characterized by …
goat and mufflons almost world-wide and is known for about 250 years. It is characterized by …
Distribution of Peripheral PrPSc in Sheep with Naturally Acquired Scrapie
MC Garza, M Monzon, B Marin, JJ Badiola, E Monleon - PloS one, 2014 - journals.plos.org
Accumulation of prion protein (PrPSc) in the central nervous system is the hallmark of
transmissible spongiform encephalopathies. However, in some of these diseases such as …
transmissible spongiform encephalopathies. However, in some of these diseases such as …
Detection, occurrence and fate of emerging contaminants in agricultural environments
A review of the literature published in 2011 including 70 papers on topics ranging from
analytical methods, to occurrence and environmental fate of emerging contaminants in …
analytical methods, to occurrence and environmental fate of emerging contaminants in …
L-BSE experimentally transmitted to sheep presents as a unique disease phenotype
MM Simmons, MJ Chaplin, T Konold, C Casalone… - Veterinary …, 2016 - Springer
Apart from prion protein genotype, the factors determining the host range and susceptiblity
for specific transmissible spongiform encephalopathy agents remain unclear. It is known that …
for specific transmissible spongiform encephalopathy agents remain unclear. It is known that …
Enhanced virulence of sheep-passaged bovine spongiform encephalopathy agent is revealed by decreased polymorphism barriers in prion protein conversion …
J Priem, JPM Langeveld, LJM van Keulen… - Journal of …, 2014 - Am Soc Microbiol
Bovine spongiform encephalopathy (BSE) can be efficiently transmitted to small ruminants
(sheep and goats) with certain prion protein (PrP) genotypes. Polymorphisms in PrP of both …
(sheep and goats) with certain prion protein (PrP) genotypes. Polymorphisms in PrP of both …
Correlation between infectivity and disease associated prion protein in the nervous system and selected edible tissues of naturally affected scrapie sheep
F Chianini, GM Cosseddu, P Steele, S Hamilton… - PLoS …, 2015 - journals.plos.org
The transmissible spongiform encephalopathies (TSEs) or prion diseases are a group of
fatal neurodegenerative disorders characterised by the accumulation of a pathological form …
fatal neurodegenerative disorders characterised by the accumulation of a pathological form …
Influence of breed and genotype on the onset and distribution of infectivity and disease-associated prion protein in sheep following oral infection with the bovine …
G McGovern, S Martin, M Jeffrey, SJ Bellworthy… - Journal of comparative …, 2015 - Elsevier
The onset and distribution of infectivity and disease-specific prion protein (PrP d)
accumulation was studied in Romney and Suffolk sheep of the ARQ/ARQ, ARQ/ARR and …
accumulation was studied in Romney and Suffolk sheep of the ARQ/ARQ, ARQ/ARR and …
Prenatal transmission of scrapie in sheep and goats: A case study for veterinary public health
DB Adams - Open Veterinary Journal, 2016 - ajol.info
Unsettled knowledge as to whether scrapie transmits prenatally in sheep and goats and
transmits by semen and preimplantation embryos has a potential to compromise measures …
transmits by semen and preimplantation embryos has a potential to compromise measures …