Cerebrovascular reactivity (CVR) MRI with CO2 challenge: a technical review

P Liu, B Jill, H Lu - Neuroimage, 2019 - Elsevier
Cerebrovascular reactivity (CVR) is an indicator of cerebrovascular reserve and provides
important information about vascular health in a range of brain conditions and diseases …

Cerebrovascular reactivity measurement using magnetic resonance imaging: a systematic review

E Sleight, MS Stringer, I Marshall, JM Wardlaw… - Frontiers in …, 2021 - frontiersin.org
Cerebrovascular reactivity (CVR) magnetic resonance imaging (MRI) probes cerebral
haemodynamic changes in response to a vasodilatory stimulus. CVR closely relates to the …

Neuroimaging of vascular reserve in patients with cerebrovascular diseases

MR Juttukonda, MJ Donahue - Neuroimage, 2019 - Elsevier
Cerebrovascular reactivity, defined broadly as the ability of brain parenchyma to adjust
cerebral blood flow in response to altered metabolic demand or a vasoactive stimulus, is …

Cerebrovascular reactivity measurement in cerebral small vessel disease: rationale and reproducibility of a protocol for MRI acquisition and image processing

MJ Thrippleton, Y Shi, G Blair… - … Journal of Stroke, 2018 - journals.sagepub.com
Background Impaired autoregulation may contribute to the pathogenesis of cerebral small
vessel disease. Reliable protocols for measuring microvascular reactivity are required to test …

Evaluation of cerebrovascular reserve in patients with cerebrovascular diseases using resting-state MRI: a feasibility study

K Taneja, H Lu, BG Welch, BP Thomas, M Pinho… - Magnetic resonance …, 2019 - Elsevier
Purpose To demonstrate the feasibility of mapping cerebrovascular reactivity (CVR) using
resting-state functional MRI (fMRI) data without gas or other challenges in patients with …

Improving the assessment of breath-holding induced cerebral vascular reactivity using a multiband multi-echo ASL/BOLD sequence

AD Cohen, Y Wang - Scientific reports, 2019 - nature.com
Breath holding (BH) is a viable vasodilatory stimulus for calculating functional MRI-derived
cerebral vascular reactivity (CVR). The BH technique suffers from reduced repeatability …

Improving the breath-holding CVR measurement using the multiband multi-echo EPI sequence

AD Cohen, AS Jagra, NJ Visser, B Yang… - Frontiers in …, 2021 - frontiersin.org
Blood oxygen level-dependent (BOLD) functional MRI (fMRI) is commonly used to measure
cerebrovascular reactivity (CVR), which can convey insightful information about …

Optimisation, evaluation and application of cerebrovascular reactivity measurement using magnetic resonance imaging in patients with cerebral small vessel disease

E Sleight - 2023 - era.ed.ac.uk
Small vessel disease (SVD) is a common cause of strokes and dementia. Currently, there
are no treatments; therefore, developing and validating early biomarkers of disease …

Dependence of resting-state-based cerebrovascular reactivity (CVR) mapping on spatial resolution

P Liu, B Hu, L Kartchner, P Joshi, C Xu… - Frontiers in …, 2023 - frontiersin.org
Cerebrovascular reactivity (CVR) is typically assessed with a carbon dioxide (CO2) stimulus
combined with BOLD fMRI. Recently, resting-state (RS) BOLD fMRI has been shown …

Quantitative myocardial first‐pass perfusion imaging of CO2‐induced vasodilation in rats

G Kwiatkowski, S Kozerke - NMR in Biomedicine, 2021 - Wiley Online Library
Inducible hypercapnia is an alternative for increasing the coronary blood flow necessary to
facilitate the quantification of myocardial blood flow during hyperemia. The current study …