Disease overview The myelodysplastic syndromes (MDS) are a very heterogeneous group
of myeloid disorders characterized by peripheral blood cytopenias and increased risk of …

Our understanding of the genetics of acute myeloid leukemia (AML) development from
myelodysplastic syndrome (MDS) has advanced significantly as a result of next-generation …

Disease overview The myelodysplastic syndromes (MDS) are a very heterogeneous group
of myeloid disorders characterized by peripheral blood cytopenias and increased risk of …

The goal of this review is to highlight recent advances in our understanding of the
pathobiology of leukemias and lymphomas. Our theme throughout will be to relate specific …

Chronic inflammation with aging (“inflammaging”) plays a prominent role in the
pathogenesis of myeloid malignancies. Aberrant inflammatory activity affects many different …

Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal disorders
characterized by ineffective hematopoiesis and frequent progression to acute myeloid …

Twenty‐five transfusion‐dependent myelodysplastic syndrome (MDS) patients (with< 20%
blasts) were treated in a phase II study with antithymocyte globulin (ATG) at 40 mg/kg/d for …

The myelodysplastic syndromes (MDSs) are common, acquired, clinically challenging
hematologic conditions that are characterized by bone marrow failure and a risk of …

More frequent skewing of X‐chromosome inactivation patterns (XCIPs) occurs in the white
blood cells of elderly females; this study was performed to determine whether this occurs in …

Studies of X chromosome inactivation patterns are central to many aspects of our
understanding of the pathogenesis of haematological malignancies. In patients with …