Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty
L Ferrucci, E Fabbri - Nature Reviews Cardiology, 2018 - nature.com
Most older individuals develop inflammageing, a condition characterized by elevated levels
of blood inflammatory markers that carries high susceptibility to chronic morbidity, disability …
of blood inflammatory markers that carries high susceptibility to chronic morbidity, disability …
HIV infection
More than 75 million people worldwide have been infected with human immunodeficiency
virus (HIV), and there are now approximately 37 million individuals living with the infection …
virus (HIV), and there are now approximately 37 million individuals living with the infection …
Comorbidities among US patients with prevalent HIV infection—a trend analysis
Objective Quantify proportion of human immunodeficiency virus (HIV)–infected patients with
specific comorbidities receiving healthcare coverage from commercial, Medicaid, and …
specific comorbidities receiving healthcare coverage from commercial, Medicaid, and …
Ageing and inflammation in patients with HIV infection
Nowadays, HIV+ patients have an expected lifespan that is only slightly shorter than healthy
individuals. For this reason, along with the fact that infection can be acquired at a relatively …
individuals. For this reason, along with the fact that infection can be acquired at a relatively …
[HTML][HTML] Age-related deficit accumulation and the diseases of ageing
K Rockwood, SE Howlett - Mechanisms of ageing and development, 2019 - Elsevier
With ageing, the potency of individual risk factors traditionally associated with common
illnesses declines. Instead, it is becoming clear that the impact of a wide range of age …
illnesses declines. Instead, it is becoming clear that the impact of a wide range of age …
The geriatric management of frailty as paradigm of “The end of the disease era”
M Cesari, E Marzetti, U Thiem… - European journal of …, 2016 - Elsevier
The sustainability of healthcare systems worldwide is threatened by the absolute and
relative increase in the number of older persons. The traditional models of care (largely …
relative increase in the number of older persons. The traditional models of care (largely …
[HTML][HTML] HIV and aging
EJ Wing - International journal of infectious diseases, 2016 - Elsevier
With the wider availability of antiretrovirals, the world's HIV population is aging. More than
10% of the 34.5 million HIV-positive individuals worldwide are over the age of 50 years and …
10% of the 34.5 million HIV-positive individuals worldwide are over the age of 50 years and …
Aging with HIV
G Guaraldi, J Milic, C Mussini - Current HIV/AIDS Reports, 2019 - Springer
Abstract Purpose of Review This review points out unmet medical needs and open research
questions of older adults living with HIV. Starting from the definition of aging in HIV, it …
questions of older adults living with HIV. Starting from the definition of aging in HIV, it …
A frailty index predicts survival and incident multimorbidity independent of markers of HIV disease severity
G Guaraldi, TD Brothers, S Zona, C Stentarelli, F Carli… - Aids, 2015 - journals.lww.com
Objectives: Aging with HIV is associated with multisystem vulnerability that might be well
characterized by frailty. We sought to construct a frailty index based on health deficit …
characterized by frailty. We sought to construct a frailty index based on health deficit …
Screening for frailty in Canada's health care system: a time for action
As Canada's population ages, frailty–with its increased risk of functional decline,
deterioration in health status, and death–will become increasingly common. The physiology …
deterioration in health status, and death–will become increasingly common. The physiology …