Fatty acid trafficking in cells affects many aspects of cellular function3). Fatty acids act both
as an energy source and as signals for metabolic regulations including gene expression …

In response to various types of environmental and cellular stress, microglia rapidly activate
and exhibit either pro-or anti-inflammatory phenotypes to maintain tissue homeostasis …

Significance: Mitochondria are the energetic, metabolic, redox, and information signaling
centers of the cell. Substrate pressure, mitochondrial network dynamics, and cristae …

Emerging data demonstrate that microglia activation plays a pivotal role in the development
of hypothalamic inflammation in obesity. Early after the introduction of a high-fat diet …

Aims Adipocyte fatty acid-binding protein (A-FABP) is an adipokine implicating in various
metabolic diseases. Elevated circulating levels of A-FABP correlate positively with poor …

Fatty acids (FAs) are of crucial importance for brain homeostasis and neural function. Glia
cells support the high demand of FAs that the central nervous system (CNS) needs for its …

Metabolic syndrome (MetS), which is characterized by insulin resistance, high blood
glucose, obesity, and dyslipidemia, is known to increase the risk of dementia accompanied …

We previously identified transient brown adipocyte-like cells associated with heterotopic
ossification (HO). These ancillary cells support new vessel synthesis essential to bone …

Hundreds of cell types form the vertebrate brain but it is largely unknown how similar cellular
repertoires are between or within species or how cell-type diversity evolves. To examine cell …

We have previously shown that a fatty acid-binding protein7 (FABP7) inhibitor ameliorates
cerebral ischemia-reperfusion injury in mice, suggesting an association between FABPs and …