Rhamnose-containing compounds: biosynthesis and applications

S Li, F Chen, Y Li, L Wang, H Li, G Gu, E Li - Molecules, 2022 - mdpi.com
Rhamnose-associated molecules are attracting attention because they are present in
bacteria but not mammals, making them potentially useful as antibacterial agents …

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: an update for 2015–2016

DJ Harvey - Mass Spectrometry Reviews, 2021 - Wiley Online Library
This review is the ninth update of the original article published in 1999 on the application of
matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of …

Exopolysaccharide, Isolated From a Novel Strain Bifidobacterium breve lw01 Possess an Anticancer Effect on Head and Neck Cancer – Genetic and Biochemical …

L Wang, Y Wang, Q Li, K Tian, L Xu, G Liu… - Frontiers in …, 2019 - frontiersin.org
Probiotic bacteria exopolysaccharides (EPS) have been recognized as molecules that
regulate immune development and have anti-inflammation and anticancer effects. Yet, these …

O-GalNAc glycosylation affects the immunogenicity of the receptor-binding domain (RBD) of SARS-CoV-2 spike protein

Y Rong, X Wang, W Mao, M Chen, S Wang… - Chemical …, 2023 - pubs.rsc.org
The spike protein of SARS-CoV-2 has been widely used as an effective vaccine
immunogen, although some limitations still remain. Herein, O-GalNAc glycosylated RBD (Tn …

Synthetic rhamnose glycopolymer cell-surface receptor for endogenous antibody recruitment

R De Coen, L Nuhn, C Perera… - …, 2019 - ACS Publications
Synthetic materials capable of engineering the immune system are of great relevance in the
fight against cancer to replace or complement the current monoclonal antibody and cell …

Biomarker-based metabolic labeling for redirected and enhanced immune response

S Li, B Yu, J Wang, Y Zheng, H Zhang… - ACS Chemical …, 2018 - ACS Publications
Installation of an antibody-recruiting moiety on the surface of disease-relevant cells can lead
to the selective destruction of targets by the immune system. Such an approach can be an …

Monophosphoryl Lipid A-Rhamnose Conjugates as a New Class of Vaccine Adjuvants

R Rohokale, J Guo, Z Guo - Journal of medicinal chemistry, 2024 - ACS Publications
Adjuvant is an integral part of all vaccine formulations but only a few adjuvants with limited
efficacies or application scopes are available. Thus, developing more robust and diverse …

pH-Responsive Metal–Organic Framework-Coated Mesoporous Silica Nanoparticles for Immunotherapy

F Duan, J Wang, Z Li, T Zhang, Z Li… - ACS Applied Nano …, 2021 - ACS Publications
Various nanovesicles loaded with tumor-associated antigens (TAAs) have been developed
for melanoma treatment. However, the slow release of antigens leads to an ineffective …

Site-Selective Functionalized PD-1 Mutant for a Modular Immunological Activity against Cancer Cells

S Fallarini, L Cerofolini, M Salobehaj, D Rizzo… - …, 2023 - ACS Publications
Targeting immune checkpoints is a well-established strategy in cancer therapy, and
antibodies blocking PD-1/PD-L1 interactions to restore the immunological activity against …

Fucosylated ubiquitin and orthogonally glycosylated mutant A28C: conceptually new ligands for Burkholderia ambifaria lectin (BambL)

S Kuhaudomlarp, L Cerofolini, S Santarsia, E Gillon… - Chemical …, 2020 - pubs.rsc.org
Two orthogonal, metal free click reactions, enabled to glycosylate ubiquitin and its mutant
A28C forming two protein scaffolds with high affinity for BambL, a lectin from the human …