Antimicrobial resistance: two-component regulatory systems and multidrug efflux pumps

GV De Gaetano, G Lentini, A Famà, F Coppolino… - Antibiotics, 2023 - mdpi.com
The number of multidrug-resistant bacteria is rapidly spreading worldwide. Among the
various mechanisms determining resistance to antimicrobial agents, multidrug efflux pumps …

The Art of War with Pseudomonas aeruginosa: Targeting Mex Efflux Pumps Directly to Strategically Enhance Antipseudomonal Drug Efficacy

A Avakh, GD Grant, MJ Cheesman, T Kalkundri, S Hall - Antibiotics, 2023 - mdpi.com
Pseudomonas aeruginosa (P. aeruginosa) poses a grave clinical challenge due to its
multidrug resistance (MDR) phenotype, leading to severe and life-threatening infections …

Design, green synthesis, and quorum sensing quenching potential of novel 2-oxo-pyridines containing a thiophene/furan scaffold and targeting a Las R gene on P …

YA Ammar, A Ragab, MA Migahed, S Al-Sharbasy… - RSC …, 2023 - pubs.rsc.org
The current trend in fighting bacteria is attacking the virulence and quorum-sensing (QS)
signals that control bacterial communication and virulence factors, especially biofilm …

Impact of Solidago virgaurea Extract on Biofilm Formation for ESBL-Pseudomonas aeruginosa: An In Vitro Model Study

AH Abdulkareem, AK Alalwani, MM Ahmed… - Pharmaceuticals, 2023 - mdpi.com
The increasing disparity between antimicrobial resistance (AMR) and the development of
new antimicrobials continues to pose a significant global health concern. However, plant …

Antibacterial and Anti-Biofilm Efficacy of Endolysin LysAB1245 against a Panel of Important Pathogens

R Soontarach, P Srimanote, SP Voravuthikunchai… - Pharmaceuticals, 2024 - mdpi.com
Infections caused by antibiotic-resistant bacteria pose a significant global challenge. This
study explores the antibacterial effects of a bacteriophage-derived endolysin, LysAB1245 …

Fecal Carriage of Colibactin-Encoding Escherichia coli Associated With Colorectal Cancer Among a Student Populace

PA Akinduti, OO Izevbigie, OA Akinduti… - Open Forum …, 2024 - academic.oup.com
Fecal carriage of the colibactin (clb) gene in Escherichia coli is described as a source that
could promote carcinogenesis, progressing to colorectal cancer. The present study …

Effluents from a university clinical analysis teaching laboratory: an inductive study on adhesion and cellular response of Pseudomonas aeruginosa

DC da Silva Amaral, H Borchardt… - Caderno …, 2024 - ojs.studiespublicacoes.com.br
Microbial resistance to antibiotics is a global threat and the World Health Organization
(WHO) predicts that future pandemics will involve resistant microorganisms. Recently, the …

[PDF][PDF] Al-Qaysi; Edan, AI; Lahij, HF Im-pact of Solidago virgaurea Extract on Biofilm Formation for ESBL-Pseudo-monas aeruginosa: An

AH Abdulkareem, AK Alalwani, MM Ahmed… - Pharm …, 2023 - researchgate.net
The increasing disparity between antimicrobial resistance (AMR) and the development of
new antimicrobials continues to pose a significant global health concern. However, plant …