Pharmacokinetic profile of chitosan modified poly lactic co-glycolic acid biodegradable nanoparticles following oral delivery of gentamicin in rabbits
Gentamicin (GM) is a well know antibiotic and drug of choice for various infections and is
available in the form of parenteral and topical formulations. Gentamicin has no oral dosage …
available in the form of parenteral and topical formulations. Gentamicin has no oral dosage …
Biodegradable nanoparticle based transdermal patches for gentamicin delivery: Formulation, characterization and pharmacokinetics in rabbits
Gentamicin, an important aminoglycoside, is water soluble and polar compound. It has
narrow therapeutic index and is potentially nephrotoxic and ototoxic. It is available in the …
narrow therapeutic index and is potentially nephrotoxic and ototoxic. It is available in the …
Mucin-grafted polyethylene glycol microparticles enable oral insulin delivery for improving diabetic treatment
M A. Mumuni, U E. Calister, N Aminu, K C. Franklin… - Applied sciences, 2020 - mdpi.com
In this study, different ratios of mucin-grafted polyethylene-glycol-based microparticles were
prepared and evaluated both in vitro and in vivo as carriers for the oral delivery of insulin …
prepared and evaluated both in vitro and in vivo as carriers for the oral delivery of insulin …
Formulation design and in vitro physicochemical characterization of surface modified self-nanoemulsifying formulations (SNEFs) of gentamicin
Self-nanoemulsifying formulations (SNEFs) structured with PEG 4000 as PEGylated SNEFs,
were formulated after solubility studies using rational blends of soybean oil, a combination of …
were formulated after solubility studies using rational blends of soybean oil, a combination of …
A new lipid-based oral delivery system of erythromycin for prolong sustain release activity
Erythromycin-loaded solid lipid microparticles (SLM) based on solidified reverse micellar
solution (SRMS) as an oral delivery formulation was studied. Hot homogenization technique …
solution (SRMS) as an oral delivery formulation was studied. Hot homogenization technique …
Development of lipid-based microsuspensions for improved ophthalmic delivery of gentamicin sulphate
Aim: Anterior eye segment disorders are treated with eye drops and ointments, which have
low ocular bioavailability necessitating the need for improved alternatives. Lipid …
low ocular bioavailability necessitating the need for improved alternatives. Lipid …
[PDF][PDF] Physicochemical characterization of artemether-entrapped solid lipid microparticles prepared from templated-compritol and Capra hircus (goat fat) homolipid
The purpose of this study was to formulate and evaluate the physicochemical properties of
artemetherloaded solid lipid microparticles (SLM) prepared from templated-compritol 888® …
artemetherloaded solid lipid microparticles (SLM) prepared from templated-compritol 888® …
Anti-inflammatory and gastroprotective properties of aspirin-entrapped solid lipid microparticles
SA Chime, PA Akpa, CC Ugwuanyi… - Recent Patents on …, 2020 - ingentaconnect.com
Background: Aspirin is a nonsteroidal anti-inflammatory drug that is very effective in the
treatment of inflammation and other health conditions, however, it causes gastric irritation …
treatment of inflammation and other health conditions, however, it causes gastric irritation …
Development, in vitro and in vivo evaluations of novel lipid drug delivery system of Newbouldia laevis (P. Beauv.)
C Umeyor, E Anaka, F Kenechukwu… - …, 2016 - journals.sagepub.com
Newbouldia laevis (P. Beauv.) is a tropical rainforest plant used in traditional folk medicine
for the treatment of malaria, cough, joint pains, stomach ache, oedema and inflammation …
for the treatment of malaria, cough, joint pains, stomach ache, oedema and inflammation …
Preliminary investigation of Ciprofloxacin-loaded microparticles for the treatment of bone diseases using coconut oil and shea butter
OD Akin-Ajani, T Awe, KA Adediran - German Journal of Pharmaceuticals …, 2023 - gjpb.de
Conventional drug delivery systems have several limitations, including poor bioavailability
and an inability to effectively transport antibiotics to the needed site of infection in the bone …
and an inability to effectively transport antibiotics to the needed site of infection in the bone …