Carotenoids, inflammation, and oxidative stress—implications of cellular signaling pathways and relation to chronic disease prevention

A Kaulmann, T Bohn - Nutrition research, 2014 - Elsevier
Several epidemiologic studies have shown that diets rich in fruits and vegetables reduce the
risk of developing several chronic diseases, such as type 2 diabetes, atherosclerosis, and …

Insights into the Dichotomous Regulation of SOD2 in Cancer

YS Kim, P Gupta Vallur, R Phaëton, K Mythreye… - Antioxidants, 2017 - mdpi.com
While loss of antioxidant expression and the resultant oxidant-dependent damage to cellular
macromolecules is key to tumorigenesis, it has become evident that effective oxidant …

Influence of doxorubicin on apoptosis and oxidative stress in breast cancer cell lines

N Pilco-Ferreto, GM Calaf - … journal of oncology, 2016 - spandidos-publications.com
Breast cancer is one of the leading causes of mortality among women worldwide due to
aggressive behavior, early metastasis, resistance to existing chemotherapeutic agent and …

Chemopreventive effects of natural dietary compounds on cancer development

MH Pan, CT Ho - Chemical Society Reviews, 2008 - pubs.rsc.org
Chemoprevention, a relatively new and promising strategy to prevent cancer, is defined as
the use of natural dietary compounds and/or synthetic substances to block, inhibit, reverse …

Manganese superoxide dismutase regulation and cancer

SK Dhar, DKS Clair - Free Radical Biology and Medicine, 2012 - Elsevier
Mitochondria are the power plants of the eukaryotic cell and the integrators of many
metabolic activities and signaling pathways important for the life and death of a cell. Normal …

Differentiation of SH-SY5Y cells to a neuronal phenotype changes cellular bioenergetics and the response to oxidative stress

L Schneider, S Giordano, BR Zelickson… - Free Radical Biology …, 2011 - Elsevier
Cell differentiation is associated with changes in metabolism and function. Understanding
these changes during differentiation is important in the context of stem cell research, cancer …

All-trans retinoic acid as a novel therapeutic strategy for Alzheimer's disease

HP Lee, G Casadesus, X Zhu, H Lee… - Expert review of …, 2009 - Taylor & Francis
Retinoic acid, an essential factor derived from vitamin A, has been shown to have a variety
of functions including roles as an antioxidant and in cellular differentiation. Since oxidative …

Production of Superoxide Anions by Keratinocytes Initiates P. acnes-Induced Inflammation of the Skin

PA Grange, C Chéreau, J Raingeaud, C Nicco… - PLoS …, 2009 - journals.plos.org
Acne vulgaris is a chronic inflammatory disorder of the sebaceous follicles.
Propionibacterium acnes (P. acnes), a gram-positive anareobic bacterium, plays a critical …

Delving into vitamin A supplementation in poultry nutrition: current knowledge, functional effects, and practical implications

Y Shastak, W Pelletier - World's Poultry Science Journal, 2024 - Taylor & Francis
Vitamin A, also known as retinol, is crucial for maintaining various physiological functions,
including vision, immunity, epithelial cell growth and differentiation, reproduction, and bone …

Dual role of superoxide dismutase 2 induced in activated microglia: oxidative stress tolerance and convergence of inflammatory responses

Y Ishihara, T Takemoto, K Itoh, A Ishida… - Journal of Biological …, 2015 - ASBMB
Microglia are activated quickly in response to external pathogens or cell debris and clear
these substances via the inflammatory response. However, excessive activation of microglia …