The protein kinase, GSK-3, participates in diverse biological processes and is now
recognized a promising drug discovery target in treating multiple pathological conditions …

Neurodegenerative disease (NDD), including Alzheimer's disease, Parkinson's disease, and
amyotrophic lateral sclerosis, are characterized by the progressive loss of neurons which …

The neuroscience community has witnessed a tremendous expansion of glia research. Glial
cells are now on center stage with leading roles in the development, maturation, and …

It was recently suggested that supplying the brain with new neurons could counteract
Alzheimer's disease (AD). This provocative idea requires further testing in experimental …

Neurogenesis, crucial for brain resilience, is reduced in Alzheimer's disease (AD) that
induces astroglial reactivity at the expense of the pro-neurogenic potential, and restoring …

Alzheimer's disease (AD) is a mostly sporadic brain disorder characterized by cognitive
decline resulting from selective neurodegeneration in the hippocampus and cerebral cortex …

Alzheimer's disease (AD) has been associated with cardiovascular and cerebrovascular risk
factors (CVRFs) during middle age and later and is frequently accompanied by …

The neural stem cell (NSC) reservoir can be harnessed for stem cell-based regenerative
therapies. Zebrafish remarkably regenerate their brain by inducing NSC plasticity in a …

Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine (ser)/threonine (Thr) kinase
that has been demonstrated to be one of the most functionally diverse kinases within …

Glycogen synthase kinase (GSK) 3β is a multifunctional serine/threonine protein kinase with
more than 100 substrates and interacting molecules. GSK3β is normally active in cells and …