The MicroRNA family gets wider: the IsomiRs classification and role

L Tomasello, R Distefano, G Nigita… - Frontiers in cell and …, 2021 - frontiersin.org
MicroRNAs (miRNAs or miRs) are the most characterized class of non-coding RNAs and are
engaged in many cellular processes, including cell differentiation, development, and …

[HTML][HTML] Genetic variation in the non-coding genome: Involvement of micro-RNAs and long non-coding RNAs in disease

B Hrdlickova, RC de Almeida, Z Borek… - Biochimica et Biophysica …, 2014 - Elsevier
It has been found that the majority of disease-associated genetic variants identified by
genome-wide association studies are located outside of protein-coding regions, where they …

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

HR Warren, E Evangelou, CP Cabrera, H Gao, M Ren… - Nature …, 2017 - nature.com
Elevated blood pressure is the leading heritable risk factor for cardiovascular disease
worldwide. We report genetic association of blood pressure (systolic, diastolic, pulse …

Life-course genome-wide association study meta-analysis of total body BMD and assessment of age-specific effects

C Medina-Gomez, JP Kemp, K Trajanoska… - The American Journal of …, 2018 - cell.com
Bone mineral density (BMD) assessed by DXA is used to evaluate bone health. In children,
total body (TB) measurements are commonly used; in older individuals, BMD at the lumbar …

miRNASNP-v3: a comprehensive database for SNPs and disease-related variations in miRNAs and miRNA targets

CJ Liu, X Fu, M Xia, Q Zhang, Z Gu… - Nucleic acids …, 2021 - academic.oup.com
MicroRNAs (miRNAs) related single-nucleotide variations (SNVs), including single-
nucleotide polymorphisms (SNPs) and disease-related variations (DRVs) in miRNAs and …

HMDD v2. 0: a database for experimentally supported human microRNA and disease associations

Y Li, C Qiu, J Tu, B Geng, J Yang, T Jiang… - Nucleic acids …, 2014 - academic.oup.com
Abstract The Human microRNA Disease Database (HMDD; available via the Web site at
http://cmbi. bjmu. edu. cn/hmdd and http://202.38. 126.151/hmdd/tools/hmdd2. html) is a …

SNPs in microRNA target sites and their potential role in human disease

A Moszyńska, M Gebert, JF Collawn… - Open …, 2017 - royalsocietypublishing.org
In the post-genomic era, the goal of personalized medicine is to determine the correlation
between genotype and phenotype. Developing high-throughput genotyping technologies …

The role of microRNAs in human diseases

KU Tüfekci, MG Öner, RLJ Meuwissen… - … : MicroRNA biology and …, 2014 - Springer
About 20 years have passed since the discovery of the first microRNA (miRNA) and by now
microRNAs are implicated in a variety of physiological and pathological processes. Since …

MirSNP, a database of polymorphisms altering miRNA target sites, identifies miRNA-related SNPs in GWAS SNPs and eQTLs

C Liu, F Zhang, T Li, M Lu, L Wang, W Yue, D Zhang - BMC genomics, 2012 - Springer
Background Numerous single nucleotide polymorphisms (SNPs) associated with complex
diseases have been identified by genome-wide association studies (GWAS) and expression …

lncRNASNP: a database of SNPs in lncRNAs and their potential functions in human and mouse

J Gong, W Liu, J Zhang, X Miao… - Nucleic acids research, 2015 - academic.oup.com
Long non-coding RNAs (lncRNAs) play key roles in various cellular contexts and diseases
by diverse mechanisms. With the rapid growth of identified lncRNAs and disease-associated …