Transplantation of human neural stem cells exerts neuroprotection in a rat model of Parkinson's disease
T Yasuhara, N Matsukawa, K Hara, G Yu… - Journal of …, 2006 - Soc Neuroscience
Neural stem cells (NSCs) possess high potencies of self-renewal and neuronal
differentiation. We explored here whether transplantation of human NSCs cloned by v-myc …
differentiation. We explored here whether transplantation of human NSCs cloned by v-myc …
Cognitive dysfunction and depression in Parkinson's disease: what can be learned from rodent models?
HS Lindgren, SB Dunnett - European Journal of Neuroscience, 2012 - Wiley Online Library
Parkinson's disease (PD) has for decades been considered a pure motor disorder and its
cardinal motor symptoms have been attributed to the loss of dopaminergic (DAergic) …
cardinal motor symptoms have been attributed to the loss of dopaminergic (DAergic) …
Therapeutic Potential of Embodied Cognition for Clinical Psychotherapies: From Theory to Practice
JMB Fugate, SL Macrine… - Cognitive Therapy and …, 2024 - Springer
Background This paper examines cognitive and body-based therapies through the lens of
embodiment, framing treatments as constructed experiences shaped by individuals' …
embodiment, framing treatments as constructed experiences shaped by individuals' …
Unilateral nigrostriatal 6-hydroxydopamine lesions in mice I: motor impairments identify extent of dopamine depletion at three different lesion sites
The unilateral 6-hydroxydopamine mouse lesion models of Parkinson's disease have
received increasing attention in recent years, but comparison of the different lesion models …
received increasing attention in recent years, but comparison of the different lesion models …
The Corridor Task: a simple test of lateralised response selection sensitive to unilateral dopamine deafferentation and graft-derived dopamine replacement in the …
E Dowd, C Monville, EM Torres, SB Dunnett - Brain research bulletin, 2005 - Elsevier
In this experiment, we report a novel drug-free behavioural test of lateralised neglect which
is sensitive to unilateral dopamine-denervating lesions and subsequent graft-derived striatal …
is sensitive to unilateral dopamine-denervating lesions and subsequent graft-derived striatal …
The 6-OHDA mouse model of Parkinson's disease–terminal striatal lesions provide a superior measure of neuronal loss and replacement than median forebrain …
V Bagga, SB Dunnett, RA Fricker - Behavioural brain research, 2015 - Elsevier
Abstract Unilateral 6-hydroxydopamine (6-OHDA) lesions of the nigrostriatal pathway
produce side-biased motor impairments that reflect the motor deficits seen in Parkinson's …
produce side-biased motor impairments that reflect the motor deficits seen in Parkinson's …
Lentivector‐mediated delivery of GDNF protects complex motor functions relevant to human Parkinsonism in a rat lesion model
E Dowd, C Monville, EM Torres… - European Journal of …, 2005 - Wiley Online Library
Although viral vector‐mediated delivery of glial cell‐line derived neurotrophic factor (GDNF)
to the brain has considerable potential as a neuroprotective strategy in Parkinson's disease …
to the brain has considerable potential as a neuroprotective strategy in Parkinson's disease …
Unilateral nigrostriatal 6-hydroxydopamine lesions in mice II: predicting l-DOPA-induced dyskinesia
In the 6-hydroxydopamine (6-OHDA) lesioned rodent the location of the lesion produces
significantly different behavioural phenotypes, responses to the dopamine precursor l-3, 4 …
significantly different behavioural phenotypes, responses to the dopamine precursor l-3, 4 …
Primary tissue for cellular brain repair in Parkinson's disease: Promise, problems and the potential of biomaterials
The dopamine precursor, levodopa, remains the “gold standard” treatment for Parkinson's
disease, and, although it provides superlative efficacy in the early stages of the disease, its …
disease, and, although it provides superlative efficacy in the early stages of the disease, its …
Portable microstimulator for chronic deep brain stimulation in freely moving rats
C Forni, O Mainard, C Melon, D Goguenheim… - Journal of neuroscience …, 2012 - Elsevier
In the last decades, deep brain stimulation (DBS) has been widely used as a functional
surgical strategy for the treatment of a variety of neurological and psychiatric disorders …
surgical strategy for the treatment of a variety of neurological and psychiatric disorders …