Background The complement system is an important arm of immune defense bringing innate
and adaptive immunity. Although originally regarded as a major complementary defense …

Background Abnormal remodelling of the extracellular matrix (ECM) has generally been
linked to pulmonary inflammation and fibrosis and may also play a role in the pathogenesis …

Background Orbital compartments harbor a variety of tissues that can be independently
targeted in a plethora of disorders resulting in sight-threatening risks. Orbital inflammatory …

Sarcoidosis is a complex, polygenic, inflammatory granulomatous multi-organ disease of
unknown cause. The granulomatous inflammation in sarcoidosis is driven by the interplay …

Background Clinical bronchoalveolar lavage fluid (BALF) samples are rich in biomolecules,
including proteins, and useful for molecular studies of lung health and disease. However …

Sarcoidosis is a multisystem disease characterized by the development and accumulation of
granulomas, the hallmark of an inflammatory process induced by environmental and/or …

Interstitial lung disease (ILD) is an umbrella term representing a heterogeneous group of
restrictive lung disorders with destructive abnormalities in the lung interstitium. The …

Ocular sarcoidosis is an inflammatory disease that manifests as uveitis, and is often difficult
to distinguish from other forms of uveitis based on nonspecific findings alone …

Sarcoidosis is a systemic granulomatous disease predominantly affecting the lungs. The
mechanisms promoting disease pathogenesis and progression are unknown, although …

A Promising Biomarker for Pulmonary Sarcoidosis That Must Cross the Finish Line Page 1 A
Promising Biomarker for Pulmonary Sarcoidosis That Must Cross the Finish Line Lisa Maier1, 2 …